“…11,13,15,18 -21 Cold intolerance has also been noticed frequently in patients with Raynaud's disease, [22][23][24][25] upper extremity fractures, 26 digital replantations, 21,[27][28][29][30][31][32][33][34][35] and after raising radial forearm flaps. 36,37 The severity of CI has been studied subjectively using a single question, 16,30,38 interviews, 10,17,29,39 questionnaires, 13,18,[32][33][34] and validated questionnaires such as the McCabe 12,[18][19][20]40 and the Blond McIndoe CISS. 11,15 In patients exposed to vibration tools (e.g., forestry workers, construction workers), Raynaud's disease, complex regional pain syndrome, or digital replantations and amputations, several laboratory tests have been used to study digital blood flow and skin temperature, for example, laser Doppler flowmetry, 31,40 -47 plethysmography to measure the amount of blood inflow, 27,34,43 finger systolic blood pressure, 26,33,48 -50 thermocouples on the skin, 4,…”