Aetiological factors and clinical profile of neonatal jaundice from a rural area of North Kerala, India

Valiyat, Shemeena; Valoor, Harsha T.; Radhamadhavan, Sayujya; Vayalil, Salina Sasi

doi:10.18203/2349-3291.ijcp20172023

Cited by 2 publications

(2 citation statements)

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“…G6PD deficiency was reported in 2.6% neonates by Merchant et al [12] and 3.4% by Narang et al [7] , where as in our study, no case of G6PD was observed. In study conducted by Shemeena Valiyat et al [15] out of 110 jaundiced neonates, 102 (92.5%) were term babies and 8 (7.3%) were preterm, 69 (62.75%) were males and 41 (37.27%) females. Physiological jaundice was seen in 44 (40%) of neonates.…”

Section: Discussionmentioning

confidence: 96%

Neonates with Jaundice A Clinical Profile

Manuel

Shajahan

2020

AJCPN

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Background: In the first week of child birth, neonatal jaundice is the most common problem which leads to delayed hospital discharge and re-admissions. Recognising early neonatal hyperbilirubenemia plays a pivotal role in preventing serious complications. The aim of this study was to study the clinical profile and the aetiological factors leading to neonatal jaundice in rural areas.Subject and Method:This study is a prospective observational study conducted in neonatal intensive care unit (NICU) and post natal ward . This study was conducted during the period of February 2017 to July 2017. Total 400 neonates were admitted in NICU and post natal ward during this period. Out of them, 100 newborns were having jaundice (Serum bilirubin > 10 mg/dl). 100 cases in total were enrolled in the study. Result:In this study,out of 100 neonates, 70% were males and 30% were females. , 92 were born at term (92%) and remaining 10 were preterm babies (10%). Physiological jaundice constituted 45%, followed by ABO incompatibility constituted 25%, followed by sepsis(1%), Rh incompatibility (8%), idioapathy (8%), prematurity (5%), cephalhematoma (4%), breast feeding (2%), haemolytic anemia (2%) were diagnosed as hereditary spherocytosis. Conclusion:Physiological jaundice is the most common cause of neonatal jaundice followed by ABO incompatibility, sepsis, Rh incompatibility and idiopathic cases. Cephalhematoma, breast feeding jaundice and haemolytic anaemia are the less common causes. Hence, it is required to monitor neonates more appropriately and accurately.

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Section: Discussionmentioning

confidence: 96%

Neonates with Jaundice A Clinical Profile

Manuel

Shajahan

2020

AJCPN

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“…Which of these n e o n a t e s w i l l e x p e r i e n c e s u b s t a n t i a l hyperbilirubinemia (Total Serum Bilirubin 15mg/dl) is difficult to predict. 3% of normal-term newborns 7,8 often have significant hyperbilirubinemia. Non-invasive, most affordable, and feasible investigation at delivery is an estimation of umbilical cord blood bilirubin (UCB).…”

Section: Diagnostic Accuracy Of Cord Blood Bilirubin In Predicting Ne...mentioning

confidence: 99%

Diagnostic Accuracy of Cord Blood Bilirubin in Predicting Neonatal Hyperbilirubinemia, Taking Neonatal Hyperbilirubinemia within One Week of Birth as Gold Standard

Majeed,

Ahmed,

Hanif

et al. 2023

L&S

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Objective: To determine the diagnostic accuracy of cord blood bilirubin in predicting neonatalhyperbilirubinemia, taking neonatal hyperbilirubinemia within one week of birth as the gold standard.Study Design: Across-sectional study.Place and Duration of Study: The Study was conducted at the Department of Pediatric Medicine, Sheikh Zayed Hospital, Rahim Yar Khan, Pakistan from 7 September 2020 to 6 March 2021.Methods: A total of 366 term neonates of both gendersgenders were included. Neonates with congenital hypothyroidism, neonatal hepatitis, biliary atresia, and sepsis were excluded. After getting informed consent from parents, a cord blood sample was taken and sent to the institutional laboratory for measuring total bilirubin levels, and neonatal hyperbilirubinemia (yes/no) was noted. All neonates were followed by the researcher for one week and neonatal hyperbilirubinemia was noted.Results: The study yielded 193 true positive and 14 false positive cases, along with 7 false negative and 152 true negative cases, with a statistically significant p-value of 0.0001. Overall, the diagnostic accuracy of cord blood bilirubin in predicting neonatal hyperbilirubinemia, using neonatal hyperbilirubinemia within one week of birth as the gold standard, was found to be 96.50% for sensitivity, 91.57% for specificity, 93.24% for positive predictive value, 95.60% for negative predictive value, and 94.26% for diagnostic accuracy.Conclusion: This study has shown that cord blood bilirubin has a rather good diagnostic accuracy for predicting newborn hyperbilirubinemia. How to cite this: Majeed M, Ahmed D, Hanif D, Khaliq H, Ahmad A, Khan ZA. Diagnostic Accuracy of Cord Blood Bilirubin in Predicting Neonatal Hyperbilirubinemia, Taking Neonatal Hyperbilirubinemia within One Week of Birth as Gold Standard. Life and Science. 2023; 4(4): 401-409. doi: http://doi.org/10.37185/LnS.1.1.347

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Aetiological factors and clinical profile of neonatal jaundice from a rural area of North Kerala, India

Cited by 2 publications

References 5 publications

Neonates with Jaundice A Clinical Profile

Neonates with Jaundice A Clinical Profile

Diagnostic Accuracy of Cord Blood Bilirubin in Predicting Neonatal Hyperbilirubinemia, Taking Neonatal Hyperbilirubinemia within One Week of Birth as Gold Standard

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