Affective cognition in bipolar disorder: A systematic review by the ISBD targeting cognition task force

Miskowiak, Kamilla Woznica; Seeberg, Ida; Kjærstad, Hanne Lie; Burdick, Katherine E.; Martínez-Àran, Anabel; Bonnín, Caterina del Mar; Bowie, Christopher R.; Carvalho, André F.; Gallagher, Peter; Hasler, Gregor; Lafer, Beny; López‐Jaramillo, Carlos; Sumiyoshi, Tomiki; McIntyre, Roger S.; Schaffer, Ayal; Porter, Richard; Purdon, Scot E.; Torres, Ivan J.; Yatham, Lakshmi N.; Young, Allan H.; Kessing, Lars Vedel; Rheenen, Tamsyn E. Van; Vieta, Eduard

doi:10.1111/bdi.12834

Cited by 86 publications

(55 citation statements)

References 146 publications

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“…Many patients with mood disorders have significant cognitive impairment upon objective assessment (Douglas et al, 2018; Miskowiak et al, 2019) that is closely linked to general functioning (Baune and Malhi, 2015; McIntyre et al, 2013) and perhaps also to the risk of relapse (Schmid and Hammar, 2013). In addition, some patients perceive that they have significant cognitive impairment.…”

Section: Aetiology and Pathogenesis Of Mood Disordersmentioning

confidence: 99%

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Malhi

Bell

Bassett³

et al. 2020

Aust N Z J Psychiatry

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Objectives: To provide advice and guidance regarding the management of mood disorders, derived from scientific evidence and supplemented by expert clinical consensus to formulate s that maximise clinical utility. Methods: Articles and information sourced from search engines including PubMed, EMBASE, MEDLINE, PsycINFO and Google Scholar were supplemented by literature known to the mood disorders committee (e.g. books, book chapters and government reports) and from published depression and bipolar disorder guidelines. Relevant information was appraised and discussed in detail by members of the mood disorders committee, with a view to formulating and developing consensus-based recommendations and clinical guidance. The guidelines were subjected to rigorous consultation and external review involving: expert and clinical advisors, key stakeholders, professional bodies and specialist groups with interest in mood disorders. Results: The Royal Australian and New Zealand College of Psychiatrists mood disorders clinical practice guidelines 2020 (MDcpg2020) provide up-to-date guidance regarding the management of mood disorders that is informed by evidence and clinical experience. The guideline is intended for clinical use by psychiatrists, psychologists, primary care physicians and others with an interest in mental health care. Conclusion: The MDcpg2020 builds on the previous 2015 guidelines and maintains its joint focus on both depressive and bipolar disorders. It provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Mood disorders committee: Gin S Malhi (Chair), Erica Bell, Darryl Bassett, Philip Boyce, Richard Bryant, Philip Hazell, Malcolm Hopwood, Bill Lyndon, Roger Mulder, Richard Porter, Ajeet B Singh and Greg Murray.

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Section: Aetiology and Pathogenesis Of Mood Disordersmentioning

confidence: 99%

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Malhi

Bell

Bassett³

et al. 2020

Aust N Z J Psychiatry

Self Cite

343

365

View full text Add to dashboard Cite

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“…Negative bias is not unique to depression. Its role is well established in a range of anxiety disorders (Davey and Meeten 2016) as well as bipolar disorder (Miskowiak et al 2018a) and schizophrenia (Marwick andHall 2008, Potvin et al 2016). Hence, changes in emotional processing may be of transdiagnostic relevance, highlighting a core process which can affect symptoms and function across disorders.…”

Section: The Cognitive Neuropsychological Hypothesis Of Antidepressanmentioning

confidence: 99%

Cognitive neuropsychological theory of antidepressant action: a modern-day approach to depression and its treatment

Godlewska

Harmer

2020

Psychopharmacology

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Depression is a leading cause of disability worldwide and improving its treatment is a core research priority for future programmes. A change in the view of psychological and biological processes, from seeing them as separate to complementing one another, has introduced new perspectives on pathological mechanisms of depression and treatment mode of action. This review presents a theoretical model that incorporated this novel approach, the cognitive neuropsychological hypothesis of antidepressant action. This model proposes that antidepressant treatments decrease the negative bias in the processing of emotionally salient information early in the course of antidepressant treatment, which leads to the clinically significant mood improvement later in treatment. The paper discusses the role of negative affective biases in the development of depression and response to antidepressant treatments. It also discusses whether the model can be applied to other antidepressant interventions and its potential translational value, including treatment choice, prediction of response and drug development.

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“…Aberrant emotional reactivity and regulation have been posited as promising endophenotypes for BD [6] that are related to impaired interpersonal and occupational functioning [7][8][9]. However, extant behavioral studies have provided conflicting findings with respect to which of these emotional cognitive domains are affected and whether such changes are state-or trait-related (for a systematic review on emotional cognition in BD, see [10]). Behavioral paradigms of selfreported emotional states in response to pleasant and aversive stimuli have generally failed to detect significant differences between remitted patients with BD and controls [11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Eye gaze and facial displays of emotion during emotional film clips in remitted patients with bipolar disorder

et al. 2020

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Background. Aberrant emotional reactivity is a putative endophenotype for bipolar disorder (BD), but the findings of behavioral studies are often negative due to suboptimal sensitivity of the employed paradigms. This study aimed to investigate whether visual gaze patterns and facial displays of emotion during emotional film clips can reveal subtle behavioral abnormalities in remitted BD patients. Methods. Thirty-eight BD patients in full or partial remission and 40 healthy controls viewed 7 emotional film clips. These included happy, sad, and neutral scenarios and scenarios involving winning, risk-taking, and thrill-seeking behavior of relevance to the BD phenotype. Eye gaze and facial expressions were recorded during the film clips, and participants rated their emotional reactions after each clip. Results. BD patients showed a negative bias in both facial displays of emotion and self-rated emotional responses. Specifically, patients exhibited more fearful facial expressions during all film clips. This was accompanied by less positive self-rated emotions during the winning and happy film clips, and more negative emotions during the risk-taking/thrill-related film clips. Conclusions. These findings suggest that BD is associated with trait-related abnormalities in subtle behavioral displays of emotion processing. Future studies comparing patients with BD and unipolar depression are warranted to clarify whether these differences are specific to BD. If so, assessments of visual gaze and facial displays of emotion during emotional film clips may have the potential to be implemented in clinical assessments to aid diagnostic accuracy.

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Affective cognition in bipolar disorder: A systematic review by the ISBD targeting cognition task force

Abstract: This is the author manuscript accepted for publication and has undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as

Cited by 86 publications

References 146 publications

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

Cognitive neuropsychological theory of antidepressant action: a modern-day approach to depression and its treatment

Eye gaze and facial displays of emotion during emotional film clips in remitted patients with bipolar disorder

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