A 79-year-old East Indian man and retired office manager, originally from Tanzania (Africa) presented with hypotension and respiratory distress requiring intensive care unit admission. His background included a medical history of type 2 diabetes, hypertension, hypercholesterolemia and chronic obstructive pulmonary disease (40 packs/year smoker). A reticulonodular chest radiograph pattern ( Figure 1A) had been identified three months earlier because of new constitutional symptoms (fatigue, weight loss, anorexia and fever) and dyspnea. He had not travelled since immigrating to Canada 30 years prior. His vital signs included an oral temperature of 35.3°C, blood pressure of 73/49 mmHg, heart rate of 113 beats/min, respiratory rate of 33 breaths/min and an oxygen saturation of 99% (inspired mixture of 31% oxygen). Pertinent physical examination findings showed a cachectic individual with splenomegaly and expiratory wheezes but no rash, clubbing or palpable lymphadenopathy. Tazobactam-piperacillin, intravenous hydrocortisone and noradrenaline infusions were commenced. His blood test results were as follows: white blood count 4.0×10 9 /L; hemoglobin level 109 g/L (normocytic); platelet count 139×10 9 /L; hyponatremia with a sodium level of 125 mmol/L; normal potassium, bicarbonate and creatinine Can