2023
DOI: 10.1002/aro2.38
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African swine fever virus E120R inhibited cGAS‐STING‐mediated IFN‐β and NF‐κB pathways

Shuai Cui,
Yang Wang,
Shiyu Chen
et al.

Abstract: African swine fever (ASF) is an acute and severe contagious disease triggered by the African swine fever virus (ASFV), which severely threatens the global swine industry. At present, no safe and efficacious vaccine has been provided to prevent and control this disease. The pathogenesis and immune evasion mechanism of ASFV are still unknown, which seriously hinders the development of safe and effective ASF vaccines. Certain proteins of ASFV involved in immunosuppression helped to evade the host innate immune re… Show more

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