The extensive experimental work on age hardening of Al‐ and Mg‐based alloys, performed by the associated groups at IFIMAT (UNCentro, Argentina) and at LNESS (Politecnico di Milano, Italy) in recent years, is discussed here in a comprehensive way, with attention to experimental procedures and to results of general validity. For Al‐based alloys, the established knowledge regarding the different action of Zn, Cu, Mg and Ag in the formation of vacancy‐solute clusters is presented. For Mg‐based alloys, the limits of positron annihilation spectroscopy are discussed on the basis of experience in progress. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)