Agaridiol, a new 1-arylpropane-1,2-diol produced byAgaricus sp.

Abstract

The new metabolite agaridiol (1) was isolated from cultures of Agaricus sp., and its structure was elucidated by mass spectrometric and NMR spectroscopic investigations. It shows moderate anti‐microbial activity against Bacillus subtilis ATCC 6633.

Antimicrobial activity of ethanol extracts ofAgaricus brasiliensisagainst mutans streptococci

“…Few investigations into the antimicrobial activity of medicinal mushrooms have been carried out, and even fewer regarding oral microorganisms (Osaki et al, 1994;Berg et al, 1999;Paccola et al, 2001;Rosa et al, 2003;Grinde et al, 2006;Faccin et al, 2007). Hence, the aim of this article is to report the antimicrobial activity of three ethanol extracts of A. brasiliensis against mutans streptococci.…”

Research Advances in Secondary Metabolites and Biological Activities of Mushroom Genus Fungi

“…In 1999, Berg et al isolated a new diol, agaridiol, from Agaricus sp. mycelium, which showed moderate antimicrobial activity against Bacillus subtilis ATCC6633, with 200 mg of the compound per 9 mm agar pore producing a zone of inhibition with a diameter of 16 mm [20].In 2011, Munkhgerel et al urea was isolated from A. silvaticus Schaeff ex. Secr substrate [2].In 2011, Ueguchi et al found N-benzoyl-L-leucine methyl ester from A. blazei substrate, which is the first time that this compound was isolated from nature [4].…”