Age‐adjusted cut‐off using the IL D‐dimer HS assay to exclude pulmonary embolism in patients presenting to emergency

Lim, Ming Sheng; Bennett, Ashwini; Chunilal, Sanjeev

doi:10.1111/imj.13992

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…In turn, Mukubo and Kawamata argue that patients suffering from rheumatoid arthritis have higher preoperative concentrations of D-dimers than patients operated due to hip joint osteoarthritis [25]. The issue undoubtedly requires further research.One should bear in mind the necessity of correction of the cut-off point, taking into account patients' age (age in years x 10 ng/over 50 years old), which can be observed in the group of patients operated due to osteoarthritis of the hip or knee [16][17][18].…”

Section: Discussionmentioning

confidence: 99%

A Comparison of Initial D-Dimers Concentration Determined in a Group of Patients With Coxarthrosis or Gonarthrosis and in a Group With Femoral Bone Fracture

Kacprzak¹,

Bytniewski²

2020

Preprint

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Introduction D-dimers are products of fibrin being degraded by thrombin, factor XIIIa and plasmin. Their blood concentration is used in clinical diagnostics for venous thromboembolism (VTE) which involves deep vein thrombosis (DVT) and pulmonary embolism (PE). Purpose Surgical operations within the femoral bone are one of the most often performed ones in orthopedic wards. In order to determine an impact of bone injury on the risk of occurrence of a thromboembolic disease we compared the preoperative concentration of D-dimers between a group of patients hospitalized due to femur fracture and a group of patients hospitalized due to coxarthrosis or gonarthrosis. Material and methods The study involved overall 404 patients, divided into two groups. The first group enrolled 283 patients who underwent elective surgery on the femoral bone: total hip replacement (THR) and total knee replacement (TKR) due to osteoarthritis of large joints. The second group enrolled 121 patients who underwent surgery due to femoral fracture. All patients underwent a physical examination for an occurrence of varicose veins in lower limbs. No clinical features of venous thromboembolism were found in patients qualified for the study, based on examination of the venous system in lower limbs, which was supplemented by ultrasound examination. Preoperative blood concentrations of D-dimers were measured in all participants. Results In patients undergoing scheduled joint replacement surgery due to coxarthrosis or gonarthrosis D-dimers concentrations ranged between 122 and 7712 ng/mL, with a mean of 822.3 ng/mL (SD 811.2 ng/mL). It was markedly lower than these found in patients with femur fracture: they ranged from 23.6 to 48340 ng/mL, mean 8793.2 ng/mL (SD ± 10358.6 ng/mL). Conclusions It is suggested that elevated D-dimers levels observed in patients with femur fracture are not associated with an increased risk of occurrence of a thromboembolic disease.

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Section: Discussionmentioning

confidence: 99%

A Comparison of Initial D-Dimers Concentration Determined in a Group of Patients With Coxarthrosis or Gonarthrosis and in a Group With Femoral Bone Fracture

Kacprzak¹,

Bytniewski²

2020

Preprint

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“…Devices based on MCPS have an emphasis on physical system design, cyberspace communication, and security measures. (Lim et al, 2018) Collaboration between medical professionals and technology improves accuracy and efficacy. Ingenious machines with computerised controls are infusion pumps of today.…”

Section: Introductionmentioning

confidence: 99%

Working Principle and Intelligence of Smart Infusion Pump

Ali¹,

Rehan

Zahid

et al. 2023

PJS

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There is a tremendous demand on the critical care resources due to the extensivespread of the ongoing coronavirus pandemic and the large number of patients requiring critical care.The efficacy of a device directly influences how long a patient lives since patients are often receivingcritical care. Smart infusion pump is a medical device that can drip fluids into the patient's body. Thisdevice is considered as one of the most safety-critical medical devices due to the way it functions andthe risks it presents. The main objective of this work is to develop an affordable infusion pump usingembedded technology. The main tactic is to develop equipment that can identify air bubbles in infusionpump tubing since even a little one might obstruct blood flow and result in mortality. This method mayprovide consumers an accurate result, making it the greatest method for identifying bubbles and savinglives.

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Age adjusted D-dimer cutoffs for pulmonary embolism in a geriatric population utilizing a D-dimer unit assay

Khan

Alter

Clayton

et al. 2022

The American Journal of Emergency Medicine

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Age‐adjusted cut‐off using the IL D‐dimer HS assay to exclude pulmonary embolism in patients presenting to emergency

Cited by 4 publications

References 18 publications

A Comparison of Initial D-Dimers Concentration Determined in a Group of Patients With Coxarthrosis or Gonarthrosis and in a Group With Femoral Bone Fracture

A Comparison of Initial D-Dimers Concentration Determined in a Group of Patients With Coxarthrosis or Gonarthrosis and in a Group With Femoral Bone Fracture

Working Principle and Intelligence of Smart Infusion Pump

Age adjusted D-dimer cutoffs for pulmonary embolism in a geriatric population utilizing a D-dimer unit assay

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