Age and Anatomical Location–Related Dermoscopic Patterns of 210 Acral Melanocytic Nevi in a Turkish Population

Emiroğlu, Nazan; Cengiz, Fatma Pelin; Onsun, Nahide

doi:10.1177/1203475417712496

Cited by 5 publications

(13 citation statements)

References 14 publications

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“…In our cohort, parallel furrow lines were the most common pattern (shown in Fig. 1), accounting for 44.0% of our lesions, in concordance with previous studies [9–11, 15, 16, 21, 22]. Interestingly, in 76 lesions (22.8%), we observed a previously undescribed dermatoscopic pattern characterized by wavy lines (shown in Fig.…”

Section: Discussionsupporting

confidence: 91%

“…Specific dermatoscopic patterns of acral nevi and acral melanoma were initially introduced by Japanese researchers and were further investigated by other research groups [2][3][4][5]. Patterns associated with acral nevi include the parallel furrow pattern, lattice-like, fibrillar, globular, and homogeneous patterns [3,4,[6][7][8][9][10][11]. In contrast, parallel ridge pattern, irregular diffuse pigmentation, and the multicomponent pattern are suggestive of acral melanoma [4,9,12].…”

Section: Introductionmentioning

confidence: 99%

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Acral Melanocytic Nevi in a High-Risk Population: Prevalence, Clinical Characteristics and Dermatoscopic Patterns

Papageorgiou,

Kyrgidis,

Ilut

et al. 2023

Dermatology

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Background: The prevalence of acral nevi and their dermatoscopic patterns have been mainly studied in Asian populations. Few data exist on the prevalence and clinico-dermatoscopic morphology of acral nevi in white populations. Objectives: The aim of this study was to assess the prevalence of acral nevi and evaluate their features in a cohort of Caucasian individuals at high risk for skin cancer. Methods: We prospectively examined the palms and soles of 680 high-risk patients who underwent total body clinical and dermatoscopic documentation, as a part of their routine follow-up, between January 2016 and March 2020 at a skin cancer referral center in Greece. Results: Overall, 334 acral lesions were detected in 217 (37.0%) of 585 patients in the study. The presence of acral nevi was associated with 2.6 higher odds of a total nevus count higher than 50 (OR: 2.6, p < 0.05, confidence intervals [CI]: 1.11–6.09). Of 334 acral nevi, 65.0% were clinically flat and 35.0% were clinically palpable. Palpable lesion had 19-fold higher probability of being located on the sole (OR: 19.44, p < 0.05, CI: 3.91–96.7). The parallel furrow pattern was present in 147 lesions (44.0%). In 76 lesions (22.8%), we observed a previously undefined pattern consisting of wavy lines, which was correlated with clinically palpable lesions (p < 0.001). The third most common pattern was homogeneous (10.5%), followed by the fibrillar (8.7%), the lattice-like (7.2%), the reticular (3.6%), and globular (3.3%). Conclusion: We observed a higher prevalence of benign acral melanocytic lesions than expected, probably related to our cohort selection of patients at high risk for developing skin cancer. Our study confirms the previously described dermatoscopic patterns and provides novel insights into the dermatoscopic morphology of acral palpable nevi, for which we described a new benign pattern consisting of wavy lines.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Acral Melanocytic Nevi in a High-Risk Population: Prevalence, Clinical Characteristics and Dermatoscopic Patterns

Papageorgiou,

Kyrgidis,

Ilut

et al. 2023

Dermatology

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“…Another common differential diagnosis of SH is acral nevus. Although acral nevus and SH may share a similar clinical appearance, it is usually not tricky to separate the two entities dermoscopically as SH does not exhibit a furrow pattern, which is the main dermoscopic pattern of acral nevi [11]. The presence of the homogenous color, satellite globules and sharp edges are the other useful clues to differentiate SH from acral nevi.…”

Section: Discussionmentioning

confidence: 99%

Subcorneal hematoma as an imitator of acral melanoma: Dermoscopic diagnosis

Elmas

Akdeniz

2019

North Clin Istanbul

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S ubcorneal hematoma (SH) means blood accumulation beneath the horny layer of the skin. SH usually occurs in the palmoplantar region as a consequence of blunt trauma. Differential diagnosis of the entity mainly includes acral lentiginous melanoma and acral nevi [1, 2]. Dermoscopy is a non-invasive and practical tool that recently has become one of the major diagnostic methods in daily dermatology practice. Dermoscopic features of many dermatological conditions have been well described. However, only one original study focusing on the dermoscopic findings of SH exists in the respective literature [1]. In this study, we aimed to describe dermoscopic findings of SH, which will facilitate the diagnosis by reducing the use of invasive procedures. MATERIALS AND METHODS This study included patients with subcorneal hematoma. All the patients were selected from the outpatient de-ABSTRACT OBJECTIVE: There are few studies investigating dermoscopic features of subcorneal hematoma, which is one of the imitators of acral melanoma. In this study, we aimed to describe dermoscopic findings of SH which will facilitate the diagnosis by reducing the use of invasive procedures. METHODS: This study included patients with subcorneal hematoma. Clinical, demographic and dermoscopic findings of all the patients were retrospectively reviewed. The diagnosis of subungual hematoma was confirmed using a positive scratch test in all of the patients. RESULTS: The findings showed that red-black (n=9, 45%) was the most common dermoscopic color followed by brown (n=4, 20%), red (n=3, 15%), black (n=2, 10%), brown-black (n=1, 5%) and red-brown (n=1, 5%). The most common pigmentation pattern was homogenous pattern (n=13, 65%). Eleven (55%) lesions showed globular pattern and eight (40%) lesions exhibit parallel ridge pattern. Eight (40%) lesions showed a combination of homogenous and globular patterns. The globules were disconnected from the homogenous pigmentation in six lesions. In two (10%) lesions, the globules were localized over the homogenous pigmentation. CONCLUSION: The presence of homogenous red to brown to black pigmentation combined with globules may lead to the correct diagnosis in a subcorneal hematoma. Scratch test may be a practical and minimal invasive diagnostic option to confirm the diagnosis in suspicious cases. To our knowledge, this is the most comprehensive study focusing on the dermoscopic aspect of the subcorneal hematoma.

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“…Second, studies were specifically focused either on inconspicuous benign-looking acral nevi (with a diagnosis mainly estimated by consensus and follow-up, in the absence of a histologic definitive histopathologic diagnosis) [ 29 , 30 , 31 , 32 , 36 , 37 , 38 , 41 , 48 , 49 , 50 , 51 ] or on acral melanomas [ 42 , 43 , 44 , 47 ]. Third, the anatomic distribution of MPPLs was rarely investigated and, in those cases, most exclusively in Eastern Asiatic and/Turkish populations, on foot plantar lesions in monocentric case studies [ 41 , 52 , 53 , 54 , 55 , 56 ]. In parallel, it seems that the knowledge regarding the peculiar “acral dermoscopic glossary” [ 28 ] is not as comprehensive as the dermoscopic glossary for body or facial lesions, being almost inadequate to cover the spectrum of aMPPLs [ 18 , 19 , 20 , 21 , 33 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ].…”

Section: Discussionmentioning

confidence: 99%

Pattern Analysis of Benign and Malignant Atypical Melanocytic Skin Lesions of Palms and Soles: Variations of Dermoscopic Features According to Anatomic Site and Personal Experience

Tognetti,

Cartocci,

Moscarella

et al. 2024

Life

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Background: The differential diagnosis of atypical melanocytic skin lesions localized on palms and soles represents a diagnostic challenge: indeed, this spectrum encompasses atypical nevi (AN) and early-stage melanomas (EN) displaying overlapping clinical and dermoscopic features. This often generates unnecessary excisions or delayed diagnosis. Investigations to date were mostly carried out in specific populations, focusing either on acrolentiginous melanomas or morphologically typical acquired nevi. Aims: To investigate the dermoscopic features of atypical melanocytic palmoplantar skin lesions (aMPPLs) as evaluated by variously skilled dermatologists and assess their concordance; to investigate the variations in dermoscopic appearance according to precise location on palms and soles; to detect the features with the strongest association with malignancy/benignity in each specific site. Methods: A dataset of 471 aMPPLs—excised in the suspect of malignancy—was collected from 10 European Centers, including a standardized dermoscopic picture (17×) and lesion/patient metadata. An anatomical classification into 17 subareas was considered, along with an anatomo-functional classification considering pressure/friction, (4 macroareas). A total of 156 participants (95 with less than 5 years of experience in dermoscopy and 61 with ≥than 5 years) from 17 countries performed a blinded tele-dermoscopic pattern analysis over 20 cases through a specifically realized web platform. Results: A total of 37,440 dermoscopic evaluations were obtained over 94 (20%) EM and 377 (80%) AN. The areas with the highest density of EM compared to AN were the heel (40.3% EM/aMPPLs) of the sole and the “fingers area” (33%EM/aMPPLs) of the palm, both characterized by intense/chronic traumatism/friction. Globally, the recognition rates of 12 dermoscopic patterns were non statistically different between 95 dermatology residents and 61 specialists: aMPPLs in the plantar arch appeared to be the most “difficult” to diagnose, the parallel ridge pattern was poorly recognized and irregular/regular fibrillar patterns often misinterpreted. Regarding the aMPPL of the “heel area”, the parallel furrow pattern (p = 0.014) and lattice-like pattern (p = 0.001) significantly discriminated benign cases, while asymmetry of colors (p = 0.002) and regression structures (p = 0.025) malignant ones. In aMPPLs of the “plantar arch”, the lattice-like pattern (p = 0.012) was significant for benignity and asymmetry of structures, asymmetry of colors, regression structures, or blue-white veil for malignancy. In palmar lesions, no data were significant in the discrimination between malignant and benign aMPPLs. Conclusions: This study highlights that (i) the pattern analysis of aMPPLs is challenging for both experienced and novice dermoscopists; (ii) the histological distribution varies according to the anatomo-functional classification; and (iii) different dermoscopic patterns are able to discriminate malignant from benign aMPPLs within specific plantar and palmar areas.

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Age and Anatomical Location–Related Dermoscopic Patterns of 210 Acral Melanocytic Nevi in a Turkish Population

Cited by 5 publications

References 14 publications

Acral Melanocytic Nevi in a High-Risk Population: Prevalence, Clinical Characteristics and Dermatoscopic Patterns

Acral Melanocytic Nevi in a High-Risk Population: Prevalence, Clinical Characteristics and Dermatoscopic Patterns

Subcorneal hematoma as an imitator of acral melanoma: Dermoscopic diagnosis

Pattern Analysis of Benign and Malignant Atypical Melanocytic Skin Lesions of Palms and Soles: Variations of Dermoscopic Features According to Anatomic Site and Personal Experience

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