Age and Persistent Use of Cardiovascular Medication After Acute Coronary Syndrome: Results from Medication Applied and Sustained Over Time

Abstract

Older patients are less likely to be persistent with EBCMs after an ACS event at 3-month follow-up. Understanding patient-reported reasons for discontinuation can influence intervention strategies to improve long-term adherence to EBCMs.

Prediction of persistence of combined evidence-based cardiovascular medications in patients with acute coronary syndrome after hospital discharge using neural networks

“…Although prior studies have suggested age-influenced adherence [2], our study did not find an association between patient age and persistence whatever the model used.…”

Evidence of poor adherence to secondary prevention after acute coronary syndromes: possible remedies through the application of new technologies

“…Insufficient knowledge about medication regimens, low motivation or forgetfulness, polypharmacy, adverse side effects, increasing age and a lack of practical support have all been implicated and may be borne in mind. [19][20][21][22][23][24] In the particular context of ACS, studies have used text or voice message reminders and telephone education to demonstrate better adherence. 34 38 39 Evidence from other chronic conditions suggests that patients are more likely to engage with technology already at their disposal (the compliance for using separate alarms, for instance, was low) and are more likely to respond to personalised education.…”

“…Patient perception of the medication regimen tallies with adherence, with those patients rating (1) high on a scale of perceived necessity of medicines prescribed for ACS and (2) low on a scale of concerns about side effects being less likely to miss doses 19. Similarly, patient-reported reasons for discontinuation of ACS medication include the belief that it was not helping with their condition 20. Patient motivation also appears a significant issue, and depression (though not anxiety) persistently correlates with lower adherence to ACS medications 21…”

“…19 Similarly, patientreported reasons for discontinuation of ACS medication include the belief that it was not helping with their condition. 20 Patient motivation also appears a significant issue, and depression (though not anxiety) persistently correlates with lower adherence to ACS medications. 21 22 Severity of depression was even associated with the extent of non-adherence in one particular study.…”

Effects of interactive patient smartphone support app on drug adherence and lifestyle changes in myocardial infarction patients: A randomized study

“…2,8 Some of the main reasons for patient non-adherence to their medication include lack of understanding of the disease and mechanisms of drug action, or simple forgetfulness. [9][10][11][12][13][14][15] New initiatives are urgently needed to improve the effectiveness of secondary prevention programs.…”