In the last decades, head and face imaging has shifted from two-dimensional (2D) representations (conventional radiography, photography) to three-dimensional (3D) techniques that can better depict the complex morphology of this part of the body, since they can provide a large number of additional anthropometric information [1][2][3]. 3D imaging systems can be divided into volumetric (computed tomography, cone beam computed tomography, magnetic resonance imaging) and optical surface instruments (laser scanning, moiré techniques, stereophotogrammetry, patterned light techniques) [4]. These last are safe and not invasive, and provide a 3D representation of the external (cutaneous) facial surface.Among all instruments, stereophotogrammetry is becoming the most diffused and used for both adults and children. Stereophotogrammetry is fast (typical scan time 2 ms), and it provides 3D photographs coupling a 3D mesh of the analyzed surface with a color facial image (texture). The technique takes photographs of the face from at least two different positions with two or more cameras (or set of cameras) at the same time. Using a previous calibration of the instrument, these coordinated photographs are combined to form a computerized stereoscopic reconstruction of the face [3,4]. Stereophotogrammetric systems have proven to be repeatable and able to provide accurate measurements [4,5].Alongside with stereophotogrammetry, some laboratories and research groups are using laser scanners. The device illuminates the object with a low-intensity laser, and digital cameras capture the images. During data acquisition, either the laser light or the face rotate to sample the entire surface; triangulation geometry provides the depth information [6]. A multicentric study showed that laser scanning and stereophotogrammetric acquisitions can provide superimposable data, that can be efficiently shared among laboratories [7]. 3D optical surface assessments can be of great value in clinical applications, at all ages of life, but especially for children where the concerns about radioprotection are maximized [3].