Age- and Stereovision-Dependent Eye–Hand Coordination Deficits in Children With Amblyopia and Abnormal Binocularity

Grant, Simon; Suttle, Catherine; Melmoth, Dean R.; Conway, Miriam L.; Sloper, John J.

doi:10.1167/iovs.14-14745

Cited by 79 publications

(105 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast to findings from other studies 5,17 stereopsis did not contribute uniquely to the prediction of measured motor skills. However, this discrepancy may be due to sampling differences in child age, as binocularity may confer increasing benefits for eye-hand coordination as children mature (3). In addition, only 11% of our sample had stereopsis, in comparison to the more even distributions of stereopsis reported for children with amblyopia 5,17 .…”

Section: Discussionmentioning

confidence: 99%

“…Multiple regression analyses suggest that strabismus 5 or reduced stereovision 4 has a greater adverse impact on fine motor performance than the degree to which the two eyes differ in acuity among children with amblyopia. However, the relative importance of stereopsis versus degree of amblyopia may vary according to the child’s age 3 , given developmental changes in reach-to-grasp strategies 6 .…”

mentioning

confidence: 99%

See 1 more Smart Citation

Motor skills of children with unilateral visual impairment in the Infant Aphakia Treatment Study

Celano

Hartmann

DuBois

et al. 2015

Develop Med Child Neuro

View full text Add to dashboard Cite

Aim To assess motor functioning in 4.5 year olds enrolled in the Infant Aphakia Treatment Study, and to determine contributions of visual acuity and stereopsis to measured motor skills. Method Children with unilateral aphakia randomized to intraocular lens (IOL) or contact lens (CL) treatment were evaluated at 4.5 years for monocular recognition visual acuity, motor skills, and stereopsis by a traveling examiner masked to treatment condition. Motor skills were assessed with the Movement ABC-2. Visual acuity was operationalized as logMAR value for treated eye, best logMAR value for either eye, and intraocular logMAR difference. Results T-tests showed no significant differences in MABC-2 scores between the IOL and CL groups. The mean total score was low (6.43; 18th percentile) compared to the normative reference group. Motor functioning was not related to visual acuity in the treated eye or to intraocular logMAR difference, but was predicted in a regression model by the better visual acuity of either eye (usually the fellow eye), even after accounting for the influence of age at surgery, examiner, orthotropic ocular alignment, and stereopsis. Interpretation Children with unilateral congenital cataract may have delayed motor functioning at 4.5 years, which may adversely affect their social and academic functioning.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Motor skills of children with unilateral visual impairment in the Infant Aphakia Treatment Study

Celano

Hartmann

DuBois

et al. 2015

Develop Med Child Neuro

View full text Add to dashboard Cite

show abstract

“…However, in dyslexia this has often been manifested in poor balance control which has been considered as reflecting a cerebellar problem (but see Stoodley & Stein, 2013 for discussion of this). In addition, abnormalities in hand-eye coordination in reaching and grasping for objects has been found in children with amblyopia and deficits in binocularity (e.g., Grant, Suttle, Melmoth, Conway, & Sloper, 2014), with these deficits being reduced in children following binocularity training.…”

Section: Introductionmentioning

confidence: 99%

The Davida Teller Award Lecture, 2016

Atkinson

2017

Journal of Vision

View full text Add to dashboard Cite

Research in the Visual Development Unit on “dorsal stream vulnerability' (DSV) arose from research in two somewhat different areas. In the first, using cortical milestones for local and global processing from our neurobiological model, we identified cerebral visual impairment in infants in the first year of life. In the second, using photo/videorefraction in population refractive screening programs, we showed that infant spectacle wear could reduce the incidence of strabismus and amblyopia, but many preschool children, who had been significantly hyperopic earlier, showed visuo-motor and attentional deficits. This led us to compare developing dorsal and ventral streams, using sensitivity to global motion and form as signatures, finding deficits in motion sensitivity relative to form in children with Williams syndrome, or perinatal brain injury in hemiplegia or preterm birth. Later research showed that this “DSV” was common across many disorders, both genetic and acquired, from autism to amblyopia. Here, we extend DSV to be a cluster of problems, common to many disorders, including poor motion sensitivity, visuo-motor spatial integration for planning actions, attention, and number skills. In current research, we find that individual differences in motion coherence sensitivity in typically developing children are correlated with MRI measures of area variations in parietal lobe, fractional anisotropy (from TBSS) of the superior longitudinal fasciculus, and performance on tasks of mathematics and visuo-motor integration. These findings suggest that individual differences in motion sensitivity reflect decision making and attentional control rather than integration in MT/V5 or V3A. Its neural underpinnings may be related to Duncan's “multiple-demand” (MD) system.

show abstract

“…Decorrelated binocular vision can have a wide-ranging impact upon aspects of visual function, including depth judgments, [33][34][35][36] visually guided reaching/grasping kinematics, 34,[37][38][39][40] obstacle negotiation, 41 and fine visuomotor tasks. 35,36,[42][43][44][45][46] Prior to this only a small number of studies have attempted to use binocular methods of measuring perceptual visual distortions.…”

mentioning

confidence: 99%

Perceptual Visual Distortions in Adult Amblyopia and Their Relationship to Clinical Features

Piano

Bex

Simmers

2015

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

PURPOSE. Develop a paradigm to map binocular perceptual visual distortions in adult amblyopes and visually normal controls, measure their stability over time, and determine the relationship between strength of binocular single vision and distortion magnitude.METHODS. Perceptual visual distortions were measured in 24 strabismic, anisometropic, or microtropic amblyopes (interocular acuity difference ‡ 0.200 logMAR or history of amblyopia treatment) and 10 controls (mean age 27.13 6 10.20 years). The task was mouse-based target alignment on a stereoscopic liquid crystal display monitor, measured binocularly five times during viewing dichoptically through active shutter glasses, amblyopic eye viewing crosshairs, fellow eye viewing single target dots (16 locations within central 58), and five times nondichoptically, with all stimuli visible to either eye. Measurements were repeated over time (1 week, 1 month) in eight amblyopic subjects, evaluating test-retest reliability. Measurements were also correlated against logMAR visual acuity, horizontal prism motor fusion range, Frisby/Preschool Randot stereoacuity, and heterophoria/heterotropia prism cover test measurement.RESULTS. Sixty-seven percent (16/24) of amblyopes had significant perceptual visual distortions under dichoptic viewing conditions compared to nondichoptic viewing conditions and dichoptic control group performance. Distortions correlated with the strength of motor fusion (r ¼ À0.417, P ¼ 0.043) and log stereoacuity (r ¼ 0.492, P ¼ 0.015), as well as near angle of heterotropic/heterophoric deviation (r ¼ 0.740, P < 0.001), and, marginally, amblyopia depth (r ¼ 0.405, P ¼ 0.049). Global distortion index (GDI, mean displacement) remained, overall, consistent over time (median change in GDI between baseline and 1 week ¼ À0.038, 1 month ¼ À0.088; x-axis Z ¼ 4.4256, P < 0.001; y-axis Z ¼ 5.0547, P < 0.001).CONCLUSIONS. Perceptual visual distortions are stable over time and associated with poorer binocular function, greater amblyopia depth, and larger angles of ocular deviation. Assessment of distortions may be relevant for recent perceptual learning paradigms specifically targeting binocular vision.

show abstract

Age- and Stereovision-Dependent Eye–Hand Coordination Deficits in Children With Amblyopia and Abnormal Binocularity

Cited by 79 publications

References 58 publications

Motor skills of children with unilateral visual impairment in the Infant Aphakia Treatment Study

Motor skills of children with unilateral visual impairment in the Infant Aphakia Treatment Study

The Davida Teller Award Lecture, 2016

Perceptual Visual Distortions in Adult Amblyopia and Their Relationship to Clinical Features

Contact Info

Product

Resources

About