Age at natural menopause in Japanese women

Racial and ethnic differences in reproductive potential across the life cycle

“…This finding contrasts with reports that have described earlier or comparable menopause in various Asian populations compared with white women in the United States and Europe (55)(56)(57)(58)(59). Of note, many of the studies of menopausal timing in Asian populations have either been descriptive without a concurrent comparison group or have suboptimally adjusted for confounding (55)(56)(57)(58)(59). Several studies evaluating onset of menopause in Hispanic populations in Mexico and South America have described menopause ranging from 45 to 48.2 years, but methodologic issues may have biased some these estimates to lower ages (60)(61)(62).…”

“…In this cross-sectional study of nearly 15,000 women, menopausal age was comparable in whites, Hispanics, blacks, and Chinese women; Japanese women experienced menopause several months later than white women (53). This finding contrasts with reports that have described earlier or comparable menopause in various Asian populations compared with white women in the United States and Europe (55)(56)(57)(58)(59). Of note, many of the studies of menopausal timing in Asian populations have either been descriptive without a concurrent comparison group or have suboptimally adjusted for confounding (55)(56)(57)(58)(59).…”

Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects

“…Takahashi et al (30) reported that menopause augments the age-related increase in arterial stiffness. The median age of menopause among Japanese women has been reported to be almost 50 years (28). We therefore divided the subjects into two groups using the threshold of 50 years of age in this study.…”

“…A stepwise multiple regression analysis was then performed to evaluate the independent determinants of the CAVI values using age, BMI, systolic BP, triglycerides, HDL cholesterol, LDL cholesterol, 1-hour postprandial glucose, HOMA-IR, eGFR and hs-CRP as covariates in both sexes. Additionally, a stepwise multiple regression analysis was performed in the younger (under 50 years of age) and older (50 years of age or older) women because the median age of menopause in Japanese women is almost 50 years (28). Comparisons of the VFA, HMW adiponectin, and hs-CRP levels according to the 1-hour postprandial glucose levels were performed using Student's t-test.…”

Reproductive Endocrinology Diseases: Hormone Replacement and Therapy for Peri/Menopause

“…The Study of Women's Health Across the Nation (SWAN), a multicenter, multiethnic, community-based cohort study of women and the menopausal transition, reported the overall median age at natural menopause to be 51.4 years, after adjustment for other factors (Gold EB, et al, 2001). Studies performed outside the United States suggest that Africans, African Americans, (Bromberger JT, et al, 1997) and Hispanics of Mexican descent experience menopause at an earlier age than Caucasian women, as opposed to Japanese (Tamada T & Iwasake H., 1995) and Malaysian (Ismael NN., 1994) women, who report a similar median age of menopause to women of European descent. Lower educational attainment and unemployment have been independently associated with earlier age at menopause (Gold EB, et al, 2001;Cramer DW, 1994 et al) and may be markers for elevated bio-psychosocial stress.…”