Age at onset of geriatric depression and sensorineural hearing deficits

Kalayam, Balu; Meyers, Barnett S.; Kakuma, Tatsuyuki; Alexopoulos, George S.; Young, Robert C.; Solomon, S; Shotland, Rochelle; Nambudiri, Draupathi E.; Goldsmith, Daniel

doi:10.1016/0006-3223(95)00175-1

Cited by 35 publications

(24 citation statements)

References 35 publications

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“…Prior research investigating the effects of hearing loss has focused on relatively more proximal outcomes such as communication impairments, health-related quality of life (HRQoL), and depression. These studies have demonstrated a consistently negative impact of hearing loss on communication (39, 51, 54, 61, 139) and HRQoL (22, 27, 37, 86, 126), and mixed effects on depressive symptoms (20, 50, 58, 67, 69, 124). Past research into hearing loss and more critical downstream domains have demonstrated possible associations with dementia (64, 129), functional activities (12, 20, 36, 122, 136), and mortality (2, 6).…”

Section: Discussionmentioning

confidence: 99%

Cochlear Implantation in Older Adults

et al. 2012

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Cochlear implants allow individuals with severe-to-profound hearing loss access to sound and spoken language. The number of older adults in the United States who are potential candidates for cochlear implantation is approximately 150,000 and will continue to increase with the aging of the population. Should cochlear implantation (CI) be routinely recommended for these older adults, and do these individuals benefit from CI? We reviewed our 12 year experience with cochlear implantation in adults ≥60 years (n = 445) at Johns Hopkins to investigate the impact of CI on speech understanding and to identify factors associated with speech performance. Complete data on speech outcomes at baseline and 1 year post-CI were available for 83 individuals. Our results demonstrate that cochlear implantation in adults ≥60 years consistently improved speech understanding scores with a mean increase of 60. 0% (S. D. 24. 1) on HINT sentences in quiet . The magnitude of the gain in speech scores was negatively associated with age at implantation such that for every increasing year of age at CI the gain in speech scores was 1. 3 percentage points less (95% CI: 0. 6 – 1. 9) after adjusting for age at hearing loss onset. Conversely, individuals with higher pre-CI speech scores (HINT scores between 40–60%) had significantly greater post-CI speech scores by a mean of 10. 0 percentage points (95% CI: 0. 4 – 19. 6) than those with lower pre-CI speech scores (HINT <40%) after adjusting for age at CI and age at hearing loss onset. These results suggest that older adult CI candidates who are younger at implantation and with higher preoperative speech scores obtain the highest speech understanding scores after cochlear implantation with possible implications for current Medicare policy. Finally, we provide an extended discussion of the epidemiology and impact of hearing loss in older adults. Future research of CI in older adults should expand beyond simple speech outcomes to take into account the broad cognitive, social, and physical functioning outcomes that are likely detrimentally impacted by hearing loss and may be mitigated by cochlear implantation.

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Section: Discussionmentioning

confidence: 99%

Cochlear Implantation in Older Adults

et al. 2012

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“…Yet, the other eight studies did not show significant differences between groups with and without hallucinations (Cole et al, 2002;Teunisse & Olde Rikkert, 2012), delusions (Kalayam et al, 1995) or psychotic disorders (Bull and Venables, 1974;Callison et al, 1974;Prager and Jeste, 1993;Viertio et al, 2014;Watt, 1981).…”

Section: Hearing Impairment: Types and Severitymentioning

confidence: 95%

Increased risk of psychosis in patients with hearing impairment: Review and meta-analyses

Linszen

Brouwer

Heringa

et al. 2016

Neuroscience & Biobehavioral Reviews

103

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“…It is also possible that (3) hearing associations with brain morphology reflect normal variation in anatomy that is associated with risk for hearing loss and/or gender effects given evidence that men are more likely to exhibit high frequency hearing loss than women (Raynor et al 2009;Lin et al 2011) and that men may exhibit relatively less auditory cortex volume than women (Rademacher et al 2001), even in early adulthood (Brun et al 2009). Clarifying these questions is important for determining the causal mechanism(s) for central auditory system declines that may influence treatment for a disorder that is growing as a major public health problem (Kalayam et al 1995;Cruickshanks et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Auditory Cortex Signs of Age-Related Hearing Loss

Eckert

Cute

Vaden

et al. 2012

JARO

190

157

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Age-related hearing loss, or presbyacusis, is a major public health problem that causes communication difficulties and is associated with diminished quality of life. Limited satisfaction with hearing aids, particularly in noisy listening conditions, suggests that central nervous system declines occur with presbyacusis and may limit the efficacy of interventions focused solely on improving audibility. This study of 49 older adults (M069.58, SD08.22 years; 29 female) was designed to examine the extent to which low and/or high frequency hearing loss was related to auditory cortex morphology. Low and high frequency hearing constructs were obtained from a factor analysis of audiograms from these older adults and 1,704 audiograms from an independent sample of older adults. Significant region of interest and voxel-wise gray matter volume associations were observed for the high frequency hearing construct. These effects occurred most robustly in a primary auditory cortex region (Te1.0) where there was also elevated cerebrospinal fluid with high frequency hearing loss, suggesting that auditory cortex atrophies with high frequency hearing loss. These results indicate that Te1.0 is particularly affected by high frequency hearing loss and may be a target for evaluating the efficacy of interventions for hearing loss.

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Age at onset of geriatric depression and sensorineural hearing deficits

Cited by 35 publications

References 35 publications

Cochlear Implantation in Older Adults

Cochlear Implantation in Older Adults

Increased risk of psychosis in patients with hearing impairment: Review and meta-analyses

Auditory Cortex Signs of Age-Related Hearing Loss

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