The purpose of the study was to identify the main trends in the primary incidence of mental disorders in the Russian Federation in 2017–2019. The analysis of indices based on statistical reports, revealed changes in the direction of the dynamics of the primary incidence of mental disorders in the Russian Federation. In 2017–2019, the indicator increased (by 7,4 %) for the first time after a years-long (2005–2017) rather intense annual decline. The increase is observed in almost all federal districts of the country. The most noticeable increase is noted in the incidence of organic mental disorders, chronic inorganic disorders, childhood psychoses, including autism, as well as in indices in the groups of children and adolescents of 0–17 years old and individuals of 60 years and older. In conclusion, it was noted that the change in the dynamics of primary incidence in the Russian Federation observed in 2017–2019 is due to a number of factors: from organizational to social ones. As the most significant of them, early diagnosis and an increase in citizens’ referral to psychiatric institutions are noted.