Age estimation through histological study of trabecular volume and cortical bone width of the iliac crest

Castillo, Rafael Fernández; Ubelaker, Douglas H.; Djorojevic, Mirjana

doi:10.1016/j.scijus.2011.09.004

Cited by 17 publications

(15 citation statements)

References 16 publications

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“…Various skeletal parts can be utilized as adult age indicators. These include: cranial sutures of the skull [2], dental wear [3], the sternal end of the first rib [4], and fourth rib [56], the pubic symphysis [7] and auricular surfaces [8] of the pelvis, and histomorphometry of the cortical bone [91011]. In this study the focus of interest is on the vertebral osteophytes.…”

Section: Introductionmentioning

confidence: 99%

“…A great deal of research has been conducted into adult age estimation, and several methods can be applied using various parts of the human skeleton [234567891011]. Key morphological changes included in these studies were those involving cranial sutures, the pubic symphysis, auricular surface, and the sternal ends of first and fourth ribs [245678].…”

Section: Introductionmentioning

confidence: 99%

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Age estimation equations using vertebral osteophyte formation in a Thai population: comparison and modified osteophyte scoring method

2019

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Age estimation from skeletal remains is an important step in forensic biological identification. The main objective of this study is to develop an age estimation equation for the Thai population from vertebral osteophytes. Each vertebra in the cervical, thoracic and lumbar segments was scored for degree of osteophyte formation. Classification was carried out in accordance with the criteria established by Snodgrass and Watanabe, and used a new modified score of the length of vertebral osteophyte for age estimation. The sample included 400 individuals (262 males, 138 females) ranging in age from 22 to 97 years. A sample of Thai vertebral columns was used, the columns being divided into the following groups of vertebrae: cervical (C2–C7), thoracic (T1–T12), and lumbar (L1–L5). Each vertebra was scored for the degree of osteophyte formation and the accumulated data was analyzed statistically. Correlation coefficients and R-squared from mean in lumbar vertebrae for females of criteria established by the method of Snodgrass and Watanabe, the new modified score by length of vertebral osteophytes were 0.801 and 0.642 ( P <0.01); 0.755 and 0.57 ( P <0.01); 0.786 and 0.618 ( P <0.01), respectively. This study presents all 23 subcategories (C2–L5) of the vertebrae to apply in real situations, showing all age estimation equations for males, females and combined sexes of unknown sex. One application of this study is age estimation when dealing with forensic cases in the Thai population.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Age estimation equations using vertebral osteophyte formation in a Thai population: comparison and modified osteophyte scoring method

2019

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“…Previous skeletal heterogeneity related studies have predominantly focused on the differences in structural and remodelling parameters of cancellous bone (Hildebrand et al, 1999, Lochmüller et al, 2008, Aaron et al, 2015), or the physical measurements of cortical composition (Boskey et al, 2016, Scerpella et al, 2016). Except for the cortical width (Dempster et al, 1993, Castillo et al, 2012), structural characteristics of the cortical bone have rarely been compared between different skeletal sites. Considering the fact that the cortical microarchitecture is complex and a considerable skeletal heterogeneity exists between the axial and appendicular subdivisions of the skeleton (Marcus et al, 2009), the analysis of cortical bone throughout the skeleton of the same individual is needed.…”

Section: Introductionmentioning

confidence: 99%

Iliac crest histomorphometry and skeletal heterogeneity in men

et al. 2017

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PurposeThe cortical characteristics of the iliac crest in male have rarely been investigated with quantitative histomorphometry. Also it is still unknown how cortical microarchitecture may vary between the iliac crest and fractures related sites at the proximal femur. We studied the microarchitecture of both external and internal cortices within the iliac crest, and compared the results with femoral neck and subtrochanteric femoral shaft sites.MethodsUndecalcified histological sections of the iliac crest were obtained bicortically from cadavers (n = 20, aged 18–82 years, males). They were cut (7 μm) and stained using modified Masson-Goldner stain. Histomorphometric parameters of cortical bone were analysed with low (× 50) and high (× 100) magnification, after identifying cortical bone boundaries using our previously validated method. Within cortical bone area, only complete osteons with typical concentric lamellae and cement line were selected and measured.ResultsAt the iliac crest, the mean cortical width of external cortex was higher than at the internal cortex (p < 0.001). Also, osteon structural parameters, e.g. mean osteonal perimeter, were higher in the external cortex (p < 0.05). In both external and internal cortices, pore number per cortical bone area was higher in young subjects (≤ 50 years) (p < 0.05) while mean pore perimeter was higher in the old subjects (> 50 years) (p < 0.05). Several cortical parameters (e.g. osteon area per cortical bone area, pore number per cortical area) were the lowest in the femoral neck (p < 0.05). The maximal osteonal diameter and mean wall width were the highest in the external cortex of the iliac crest (p < 0.05), and the mean cortical width, osteon number per cortical area were the highest in the subtrochanteric femoral shaft (p < 0.05). Some osteonal structural parameters (e.g. min osteonal diameter) were significantly positively correlated (0.29 ≤ R2 ≤ 0.45, p < 0.05) between the external iliac crest and the femoral neck.ConclusionsThis study reveals heterogeneity in cortical microarchitecture between the external and internal iliac crest cortices, as well as between the iliac crest, the femoral neck and the subtrochanteric femoral shaft. Standard iliac crest biopsy does not reflect accurately cortical microarchitecture of other skeletal sites.

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“…These have focussed on the premise that intracortical porosity of bone and bone remodelling increases with age, and assessment of correlation between known chronological age and characteristics of histomorphological p-3 bone features, such as primary and secondary osteon numbers/size/maturitylevel, trabecular volume and cortical width [4][5][6][7][8][9][10][11][12]. These methods have been found to be of only limited value as errors for age estimation exceeded ±8 years in over half of the cases in these studies.…”

Section: Introductionmentioning

confidence: 99%

Determining ‘age at death’ for forensic purposes using human bone by a laboratory-based biomechanical analytical method

Zioupos

Williams

Christodoulou

et al. 2014

Journal of the Mechanical Behavior of Biomedical Materials

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Age estimation through histological study of trabecular volume and cortical bone width of the iliac crest

Cited by 17 publications

References 16 publications

Age estimation equations using vertebral osteophyte formation in a Thai population: comparison and modified osteophyte scoring method

Age estimation equations using vertebral osteophyte formation in a Thai population: comparison and modified osteophyte scoring method

Iliac crest histomorphometry and skeletal heterogeneity in men

Determining ‘age at death’ for forensic purposes using human bone by a laboratory-based biomechanical analytical method

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