Age-, gender-, and socioeconomic status-specific incidence of Parkinson's disease and parkinsonism in North East Scotland: The PINE study

Caslake, Robert; Taylor, Kate; Scott, Norman; Gordon, Joanna Clodagh; Harris, Clare; Wilde, Katie; Murray, Alison; Counsell, Carl

doi:10.1016/j.parkreldis.2013.01.014

Cited by 88 publications

(74 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gender differences are associated with many neurological disorders including epilepsy [1][2][3][4] , and are involved in its diagnosis and treatment. For example, the prevalence of epilepsy is higher in men than in women [5] ; men are more vulnerable to seizure-associated brain damage than women [6] ; and gender differences may influence the treatment effect of anticonvulsants [7,8] .…”

Section: Introductionmentioning

confidence: 99%

Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures

Dai

Feng

et al. 2014

Neurosci. Bull.

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures

Dai

Feng

et al. 2014

Neurosci. Bull.

View full text Add to dashboard Cite

“…Of all the studies, 16 were performed in Europe [5,7,8,10,12,14,[18][19][20][21][22][23][24][25][26][27] , 5 in Asia [9,15,16,28,29] , 4 in North America [11,13,17,30] , 1 in Australia [31] , and 1 in South America [6] (online suppl. material 3 for table of included studies).…”

Section: Resultsmentioning

confidence: 99%

The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis

Hirsch

Jetté²,

Frolkis³

et al. 2016

Neuroepidemiology

550

314

View full text Add to dashboard Cite

Background: Parkinson's disease (PD) is a common neurodegenerative disorder. Epidemiological studies on the incidence of PD are important to better understand the risk factors for PD and determine the condition's natural history. Objective: This systematic review and meta-analysis examine the incidence of PD and its variation by age and gender. Methods: We searched MEDLINE and EMBASE for epidemiologic studies of PD from 2001 to 2014, as a previously published systematic review included studies published until 2001. Data were analyzed separately for age group and gender, and meta-regression was used to determine whether a significant difference was present between groups. Results: Twenty-seven studies were included in the analysis. Meta-analysis of international studies showed rising incidence with age in both men and women. Significant heterogeneity was observed in the 80+ group, which may be explained by methodological differences between studies. While males had a higher incidence of PD in all age groups, this difference was only statistically significant for those in the age range 60-69 and 70-79 (p < 0.05). Conclusion: PD incidence generally increases with age, although it may stabilize in those who are 80+.

show abstract

“…Incidence rates are also low for those aged 50‐59 and increase sharply afterward. Age‐specific peaks differ between studies, however, ranging from 80.4 to 678 new cases/100 000 person‐years 11, 12, 13, 14, 15, 16, 17, 18, 19. German data on prevalence and incidence are rare, outdated, and had been designed primarily as door‐to‐door surveys 1.…”

Section: Introductionmentioning

confidence: 99%

Parkinson's disease in Germany: prevalence and incidence based on health claims data

2016

View full text Add to dashboard Cite

BackgroundIn Germany, epidemiological information on Parkinson's disease (PD) is rare and outdated. Considering aging populations, current prevalences and incidence rates about this age‐related disease would be important for adequate public health planning.MethodsWe used newly available health claims data sets from the largest German health insurer dating 2004‐2007 and 2007‐2010 with an analysis population in the base years of 491 038 persons aged 50 and older. Quarter‐specific information about ICD‐10 diagnoses and PD drug prescriptions from the inpatient and outpatient sectors was used to validate PD cases. Estimations were presented for two validation strategies relying on repeated PD diagnoses (SIa) and on one PD diagnosis followed by at least one PD drug prescription (SIb).ResultsThe standardized prevalence was 797 (SIb) to 961/100 000 persons (SIa), showing an age‐specific increase up to category 85‐89 and a decline thereafter. The standardized incidence rate was 192 to 229/100 000 person‐years with a similar age‐specific shape. Prevalences and incidences rates were higher for men compared to women in regard to age.ConclusionsHealth claims data are found to be suitable for PD assessment using the repeated diagnoses or PD drug prescriptions as necessary criteria.

show abstract

Age-, gender-, and socioeconomic status-specific incidence of Parkinson's disease and parkinsonism in North East Scotland: The PINE study

Cited by 88 publications

References 30 publications

Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures

Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures

The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis

Parkinson's disease in Germany: prevalence and incidence based on health claims data

Contact Info

Product

Resources

About