Age-related changes in blood biochemical composition of Hu sheep

Abdelsattar, Mahmoud M.; Vargas‐Bello‐Pérez, Einar; Zhang, Naifeng

doi:10.1080/1828051x.2022.2108730

Cited by 8 publications

(4 citation statements)

References 79 publications

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“…The level of TP was shown to be considerably positive association with ALB, These findings are corroborate with estimates by Ref. [ 53 ] reported a significant positive correlation between ALB and TP of Hu sheep. Though, it was exhibited that TP and A/G ratio had a significant negative correlation.…”

Section: Discussionsupporting

confidence: 91%

Nutritional response to water hyacinth (Eichhornia crassipes) challenges via blood biochemical profiles in goats and sheep

Fanta,

Kechero,

Yemane

2024

Heliyon

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Section: Discussionsupporting

confidence: 91%

Nutritional response to water hyacinth (Eichhornia crassipes) challenges via blood biochemical profiles in goats and sheep

Fanta,

Kechero,

Yemane

2024

Heliyon

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“…In sheep, body water content decreases and body fat content increases with increasing age (Searle, 1970). Although plasma protein concentrations in newborns are generally reported to be low, plasma albumin levels in 1‐month and 12‐month‐old sheep are similar (Abdelsattar et al, 2022; Carlos et al, 2015; Tohamy, 2011). However, it was reported that cefquinome binding to plasma proteins increased from 8% to 13% in 12‐month‐old sheep compared to 1‐month‐old sheep (Tohamy, 2011).…”

Section: Discussionmentioning

confidence: 99%

Age‐related changes in the pharmacokinetics of meloxicam after intravenous administration in sheep

Coskun,

Corum,

Durna Corum

et al. 2023

Vet Pharm & Therapeutics

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The pharmacokinetics of meloxicam was studied in 1‐, 6‐, and 12‐month‐old sheep following a single intravenous (i.v.) dose of 1 mg/kg. The experiments were carried out when the Romanov sheep were 1 month old (7.93 ± 0.91 kg), 6 months old (27.47 ± 4.91 kg), and 12 months old (37.10 ± 3.64 kg). Meloxicam concentration in plasma was determined by high‐performance liquid chromatography and the data collected were evaluated by non‐compartmental kinetic analysis. Meloxicam was detected in the plasma up to 72 h following i.v. administration in all age groups. The volume of distribution at steady state (Vdss) and total body clearance (ClT) were significantly higher in 1‐month‐old (304.87 mL/kg and 16.57 mL/h/kg) than in 12‐month‐old (193.43 mL/kg and 10.50 mL/h/kg) sheep. The area under the concentration–time curve from 0 to 72 h value of meloxicam was lower in 1‐month‐old (58.51 h*μg/mL) compared to 12‐month‐old (92.59 h*μg/mL) sheep. There was no difference in t1/2ʎz value in different age groups. The body extraction ratio values for meloxicam ranged from 0.0186 to 0.0719 after i.v. administration in all age groups. Meloxicam showed an increase in plasma concentration and a decrease in Vdss and ClT in 12‐month‐old compared to 1‐month‐old sheep. Compared to 1‐month‐old and 12‐month‐old sheep, there was no difference in these parameters in 6‐month‐old sheep. Because the age of sheep has an influence on the pharmacokinetics of meloxicam, dosage apparently may need to be adjusted for age.

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“…The lower TP in the CON group indicates poorer health condition of mutton sheep, which increases the proportion of protein dealing with harsh environments or immune depletion and it is not conducive to improving nutrient utilization. On the other hand, ALB in sheep blood is correlated significantly and positively with TP (51). It is a marker of liver function, and higher Effects of oligosaccharide chelated organic trace minerals on jejunal digestive enzymes in mutton sheep.…”

Section: Discussionmentioning

confidence: 99%

Effects of organic trace minerals chelated with oligosaccharides on growth performance, blood parameters, slaughter performance and meat quality in sheep

Zhang,

Wei,

Zhou

et al. 2024

Front. Vet. Sci.

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The present study assessed the effects of oligosaccharide-chelated organic trace minerals (OTM) on the growth performance, digestive enzyme activity, blood parameters, slaughter performance, and meat quality indexes of mutton sheep. A total of 60 East Ujumuqin × small-tailed Han crossbred mutton sheep were assigned to two groups (10 duplicates per group) by body weight (26.12 ± 3.22 kg) according to a completely randomized design. Compared to the CON group, the results of the OTM group showed: (1) no significant changes in the initial body weight, final body weight, dry matter intake, average daily gain, and feed conversion ratio (p > 0.05); (2) the activities of trypsin, lipase, and amylase in the jejunum were significantly increased (p < 0.05); (3) serum total protein, albumin, and globulin of the blood were significantly increased (p < 0.05), and the growth factor interleukin IL-10 was significantly higher (p < 0.05), while IL-2, IL-6, and γ-interferon were significantly lower (p < 0.05). Immunoglobulins A, M, and G were significantly higher (p < 0.05); (4) the live weight before slaughter, carcass weights, dressing percentage, eye muscle areas, and GR values did not differ significantly (p > 0.05); (5) shear force of mutton was significantly lower (p < 0.05), while the pH45min, pH24h, drip loss, and cooking loss did not show a significant difference (p > 0.05). The content of crude protein was significantly higher (p < 0.05), while the ether extract content was significantly reduced (p < 0.05), but no significant difference was detected between moisture and ash content; (6) the total amino acids, essential amino acids, semi-essential amino acids, and umami amino acids were significantly increased (p < 0.05). Although umami amino acids were not significant, the total volume increased (p > 0.05). Among these, the essential amino acids, threonine, valine, leucine, lysine in essential amino acids and arginine were significantly increased (p < 0.05). Also, non-essential amino acids, glycine, serine, proline, tyrosine, cysteine, and aspartic acid, were significantly higher (p < 0.05). The content of alanine, aspartate, glutamic acid, phenylalanine, and tyrosine in umami amino acids was significantly higher (p < 0.05).

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Age-related changes in blood biochemical composition of Hu sheep

Cited by 8 publications

References 79 publications

Nutritional response to water hyacinth (Eichhornia crassipes) challenges via blood biochemical profiles in goats and sheep

Nutritional response to water hyacinth (Eichhornia crassipes) challenges via blood biochemical profiles in goats and sheep

Age‐related changes in the pharmacokinetics of meloxicam after intravenous administration in sheep

Effects of organic trace minerals chelated with oligosaccharides on growth performance, blood parameters, slaughter performance and meat quality in sheep

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