Age-related changes in cortical and trabecular bone mineral status: A quantitative CT study in lumbar vertebrae

Tanno, Munehiko; Horiuchi, Tetsuya; Nakajima, Izumi; Maeda, Sérgio Setsuo; Igarashi, Mitsuo; Yamada, Hideo

doi:10.1080/028418501127346396

Cited by 6 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering the effects of bone metabolism and menopause, these factors generally were considered to be disadvantageous for bone regeneration. 45,46 However, sufficient efficacy was confirmed in this clinical trial, and it was considered that the influence of age and sex was low. Also, as bone grafting to the alveolar cleft defect is mainly used in children, OCP/Col has been used for young patients and the effect was confirmed in this clinical trial.…”

Section: Discussionmentioning

confidence: 73%

Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery

et al. 2020

View full text Add to dashboard Cite

Octacalcium phosphate and its collagen composite have been recognized as bone substitute materials possessing osteoconductivity and biodegradation properties. We evaluated the effectiveness of octacalcium phosphate and its collagen composite used for bone augmentation in major oral and maxillofacial surgeries in a clinical trial. Octacalcium phosphate and its collagen composite were used in cases of sinus floor elevation in 1- and 2-stage, socket preservation, cyst, and alveolar cleft procedures. A total of 60 patients were evaluated for effectiveness after the implantation of octacalcium phosphate and its collagen composite. Although sinus floor elevation in 1-stage, cyst, and alveolar cleft cases met the criteria for the judgment of success, sinus floor elevation in 2-stage and socket preservation groups did not meet the criteria in the initial evaluation. However, an additional evaluation for reconfirmation revealed the effectiveness of octacalcium phosphate and its collagen composite in those groups, and all evaluation results ultimately indicated the success of this clinical trial. Therefore, this clinical trial suggested that application of octacalcium phosphate and its collagen composite for oral and maxillofacial surgery was safe and effective and that octacalcium phosphate and its collagen composite could be a bone substitute candidate instead of autologous bone.

show abstract

Section: Discussionmentioning

confidence: 73%

Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Several radiographic procedures are widely used to assess age and bone health status and they yield several traits that characterize different aspects of bone aging. One of the main traits is bone mineral density (BMD), which may serve as an objective estimate of the degree of bone loss, thereby comprising an indirect measure of individual aging (Tanno et al, 2001). The bone geometry score entails caliper measurement of bone size and proportion, such as determining cortical bone thickness from a plane radiograph (Garn, 1970;Plato and Norris, 1979;Kaur and Jit, 1990).…”

mentioning

confidence: 99%

Interrelationship between bone aging traits and basic anthropometric characteristics

Kalichman

Kobyliansky

Livshits

2002

American J Hum Biol

View full text Add to dashboard Cite

Using plain hand radiographs, the age dependence of various bone-aging traits (bone mineral density [BMD], cortical index [CI], osteoarthritis [OA], and osseographic [OSS] scores) was evaluated to test whether the correlation among these traits is an individual- or population-based phenomenon. In addition, the effect of anthropometric features on variation of bone-aging traits was estimated. The study included 1,295 individuals from Chuvasha, Russia, 18 to 89 years. BMD was measured from the compact compartment of the middle and distal phalanges of both 3(rd) fingers. The CI of the II-IV metacarpal bones and II-IV proximal phalanges was obtained. The development of OA was based on the standard Kellgren and Lawrence grading scheme for 28 hand joints. OSS score, a surrogate measure that takes into account different kinds of bone changes, was also obtained for each individual. Body weight and height, eight skinfold thicknesses on the trunk and extremities, and breadths of the long bones were measured. Sex-based univariate analyses and multivariate statistical analysis showed the following: 1) Age dependence was defined more strongly in "OA-linked" compared to "osteoporosis (OP)-linked" traits; 2) While "OP-linked" bone-aging traits correlated with age differently between sexes, "OA-linked" traits did not; 3) The strong interrelationship between OA-linked and OP-linked traits in both sexes became very weak and statistically insignificant (P > 0.10) after adjustment for age. Thus, OA and OP conditions in the same individual develop independently and probably reflect different underlying physiological mechanisms. 4) Anthropometric characteristics were significantly correlated with bone-aging traits, but correlations were low (r < 0.20). Thus, the contribution of anthropometric characteristics to the rate and pattern of bone aging of the hand was to relatively small.

show abstract

Bone loss in elderly men: increased endosteal bone loss and stable periosteal apposition. The prospective MINOS study

Szulc

Delmas

2007

Osteoporos Int

View full text Add to dashboard Cite

Introduction Longitudinal studies on the age-related bone loss in men concerns the decrease in areal bone mineral density (aBMD), which can be qualified as "apparent bone loss" because it does not reflect the change in bone mineral content (BMC). Loss of BMC can be referred to as "net bone loss" because it does not take into account the morphological basis of the bone loss (decreased periosteal apposition; endosteal bone loss, i.e. bone loss on the trabecular, endocortical and intracortical surfaces). The aim of this study was to assess age-related apparent net and endosteal bone loss as well as their morphological basis and age-related changes during a prospective follow-up in a large cohort of elderly men. Methods This analysis was performed in 725 men aged 51-85 at baseline who were followed up for 90 months. Results Bone densitometry was carried out at the lumbar spine, hip and whole body by using the HOLOGIC QDR1500 device and at the distal forearm by using the Osteometer DTX100 device. Sixty-five men who abandoned the study after the first examination were older and had lower aBMC at most sites of measurement. Apparent bone loss was significant at the hip, distal forearm and whole body. Net bone loss was also significant at these sites, except for the femoral neck. Periosteal expansion was significant at all sites of measurement. Apparent and net bone loss accelerated with age, whereas the rate of periosteal expansion remained stable. At the distal radius and ulna, endosteal bone loss accelerated with age, whereas the rate of periosteal apposition remained stable. Conclusion In a large cohort of elderly men, age-related apparent bone loss (aBMD) at the hip, distal forearm and whole body was determined by the net bone loss (BMC), except for the femoral neck. Apparent and net bone loss accelerated with age, whereas the periosteal expansion rate (bone widening) remained constant. At the distal forearm, age-related acceleration of the apparent bone loss was determined by the higher endosteal bone loss, whereas the periosteal apposition rate (estimated mass of deposited bone) remained constant.

show abstract

Age-related changes in cortical and trabecular bone mineral status: A quantitative CT study in lumbar vertebrae

Cited by 6 publications

References 15 publications

Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery

Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery

Interrelationship between bone aging traits and basic anthropometric characteristics

Bone loss in elderly men: increased endosteal bone loss and stable periosteal apposition. The prospective MINOS study

Contact Info

Product

Resources

About