Age-related changes in pituitary/thyroid function in chickens

Carr, Bruce L.; Chiasson, Robert B.

doi:10.1016/0016-6480(83)90238-1

Cited by 7 publications

(2 citation statements)

References 14 publications

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“…Besides a reduction in the number of NSC observed in the aged brain, the phenomenon of decreased neurogenesis could also involve a decrease in TH availability. Decreased levels of circulating TH occur with ageing in humans (Chakraborti et al, 1999) and rodents (Cao et al, 2012), and have also been observed in non-mammals, including birds (Carr and Chiasson, 1983). Many studies have shown declines in the hippocampal process of spatial memory assimilation in aged humans, rodents, or monkeys (Foster et al, 2012;Jiang et al, 2016).…”

Section: Roles Of Th In the Ageing Brainmentioning

confidence: 97%

Comparative approaches to understanding thyroid hormone regulation of neurogenesis

Gothié

Demeneix

Remaud

2017

Molecular and Cellular Endocrinology

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Thyroid hormone (TH) signalling, an evolutionary conserved pathway, is crucial for brain function and cognition throughout life, from early development to ageing. In humans, TH deficiency during pregnancy alters offspring brain development, increasing the risk of cognitive disorders. How TH regulates neurogenesis and subsequent behaviour and cognitive functions remains a major research challenge. Cellular and molecular mechanisms underlying TH signalling on proliferation, survival, determination, migration, differentiation and maturation have been studied in mammalian animal models for over a century. However, recent data show that THs also influence embryonic and adult neurogenesis throughout vertebrates (from mammals to teleosts). These latest observations raise the question of how TH availability is controlled during neurogenesis and particularly in specific neural stem cell populations. This review deals with the role of TH in regulating neurogenesis in the developing and the adult brain across different vertebrate species. Such evo-devo approaches can shed new light on (i) the evolution of the nervous system and (ii) the evolutionary control of neurogenesis by TH across animal phyla. We also discuss the role of thyroid disruptors on brain development in an evolutionary context.

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Section: Roles Of Th In the Ageing Brainmentioning

confidence: 97%

Comparative approaches to understanding thyroid hormone regulation of neurogenesis

Gothié

Demeneix

Remaud

2017

Molecular and Cellular Endocrinology

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“…The cAMP-PK pool (+cAMP) may be a factor of age and sex (Carr and Chiasson, 1983), but the activity ratio (-cAMP/ +cAMP) is elevated in response to the activation of specific membrane receptors. Pituitary cAMP-PK activity ratio increases in response to thyrotropin-releasing hormone (TRH) stimulation (Carr and Chiasson, 1983) but not goitrogen treatment (Chiasson and Combest, 1979). In contrast, thyroid protein kinase is elevated in response to goitrogen treatment (Chiasson and Combest, 1979).…”

Section: Introductionmentioning

confidence: 99%

Some Effects of Photoperiod on the Pituitary/Thyroid Axis of Castrated Cockerels

Chiasson

Carr

1985

Poultry Science

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Pituitary cyclic adenosine monophosphate-dependent protein kinase (cAMP-PK) activity ratios of castrated cockerels on a short photoperiod are highest 2 weeks after testosterone removal in castrated birds and remain high through a 3rd week. Castrated cockerels on long photoperiods have a decline in cAMP-PK activity ratios after an elevation at 1 week following testosterone removal. This is interpreted to mean that the pituitaries of cockerels on short photoperiods are sensitive to testosterone inhibition but that this sensitivity disappears in long photoperiod-stimulated birds. Long daylengths also appear to enhance thyroid activity in castrated cockerels, although thyroid cAMP-PK activity ratios increase in the thyroid of all cockerels following the removal of testosterone (castration). These results suggest that testosterone has an inhibitory effect on both the pituitary and thyroid glands.

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The effects of castration and/or methimazole feeding on the pituitary response to temperature extremes by cockerels

Chiasson

Carr

1985

General and Comparative Endocrinology

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Age-related changes in pituitary/thyroid function in chickens

Cited by 7 publications

References 14 publications

Comparative approaches to understanding thyroid hormone regulation of neurogenesis

Comparative approaches to understanding thyroid hormone regulation of neurogenesis

Some Effects of Photoperiod on the Pituitary/Thyroid Axis of Castrated Cockerels

The effects of castration and/or methimazole feeding on the pituitary response to temperature extremes by cockerels

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