Age-Related Changes of Ag, Co, Cr, Fe, Hg, Rb, Sb,Sc, Se, and Zn Contents in Intact Thyroid of Males Investigated by Neutron Activation Analysis

Zaichick, Vladimir

doi:10.19080/ctbeb.2017.04.555644

Cited by 33 publications

(49 citation statements)

References 31 publications

(35 reference statements)

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“…The ratios of means and the difference between mean values of Br, Ca, Cl, I, K, Mg, Mn, and Na mass fractions in normal thyroid of females and males are presented in Table 4. Because, in our previous studies age-dependents of many ChE in thyroid gland was found [51][52][53][54], the comparison between ChE contents in thyroid of females and males separately in age group 1 and in age group 2 was also performed (Tables 5 & 6). The data of inter-correlation calculations (values of r -coefficient of correlation) including all ChE identified by us in thyroid of females and males separately are presented in Table 7.…”

Section: Resultsmentioning

confidence: 99%

Possible Role of Inadequate Quantities of Intra-Thyroidal Bromine, Calcium and Magnesium in the Etiology of Female Subclinical Hypothyroidism

Vladimir¹

2018

IGWHC

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Objective: Subclinical hypothyroidism does affect fertility. The prevalence of subclinical hypothyroidism is 10-15 times more common in women than in men. Many chemical elements play important role in thyroid function and fertility. The aim of this exploratory study was to evaluate whether significant differences of chemical element contents exist between female and male thyroids and how they can be related to the etiology of subclinical hypothyroidism.Methods: Thyroid tissue levels of Br, Ca, Cl, I, K, Mg, Mn, and Na were prospectively evaluated in 105 healthy persons (33 females and 72 males). Tissue samples were used for chemical element measurements, employing instrumental neutron activation analysis with high resolution spectrometry of short-lived radionuclides.Results: It was found that the Br thyroid content of females was significantly higher than that of males, while the Ca and Mg contents were lower. Conclusion:Inappropriate content of intra-thyroidal Br, Ca and Mg can be associated with the etiology of female subclinical hypothyroidism.

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Section: Resultsmentioning

confidence: 99%

Possible Role of Inadequate Quantities of Intra-Thyroidal Bromine, Calcium and Magnesium in the Etiology of Female Subclinical Hypothyroidism

Vladimir¹

2018

IGWHC

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“…In our previous study a significant positive correlation between age and some trace element contents in the thyroid was observed [23][24][25][26][27][28]. For example, a strongly pronounced tendency of age-related increase in bromine (Br), coper (Cu), rubidium (Rb) and zinc (Zn) mass fraction was demonstrated by us using 109 Cd radionuclide-induced energy dispersive X-ray fluorescent (EDXRF) analysis [26,28].…”

Section: Introductionmentioning

confidence: 87%

Trace Element Contents in Thyroid Cancer Investigated by Energy Dispersive X-Ray Fluorescent Analysis

2018

AJOCRR

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Background:Thyroid cancer is an internationally important health problem. The aim of this exploratory study was to evaluate whether significant changes in the thyroid tissue levels of Br, Cu, Fe, Rb, Sr, and Zn exist in the malignantly transformed thyroid. Methods:Thyroid tissue levels of six trace elements (Br, Cu, Fe, Rb, Sr, and Zn) were prospectively evaluated in 41 patients with thyroid malignant tumors and 105 healthy inhabitants. Measurements were performed using 109Cd radionuclide-induced energy-dispersive X-ray fluorescent analysis Tissue samples were divided into two portions. One was used for morphological study while the other was intended for trace element analysis.Results: It was found that contents of Br, Cu, and Rb were significantly higher (approximately 10, 3.4, and 1.4 times, respectively) and content of Zn were slightly, but significantly, lower (25%) in cancerous tissues than in normal tissues. http://escipub.com/american-journal-of-cancer-research-and-reviews/ 0002 Conclusions

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“…A vertical channel of the WWR-c research nuclear reactor (Branch of Karpov Institute, Obninsk).was applied to determine the content of Ag, Co, Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn by INAA-LLR. Details of used neutron flux, nuclear reactions, radionuclides, gamma-energies, and spectrometric unit were presented in our earlier publications concerning the INAA-LLR of ChE contents in human thyroid, scalp hair, and prostate [29,30,51,54].…”

Section: Sample Preparation and Methodsmentioning

confidence: 99%

“…Level of I in the normal thyroid was investigated in relation to age, gender and some non-thyroidal diseases [23,24]. After that, variations of ChE content with age in the thyroid of males and females were studied and age-and gender-dependence of some ChE was observed [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41]. Furthermore, a significant difference between some ChE contents in normal and cancerous thyroid was demonstrated [42][43][44][45][46][47].…”

Section: Introductionmentioning

confidence: 99%

Determination of twenty chemical element contents in normal and goitrous thyroid using X-ray fluorescent and neutron activation analysis

Zaichick¹

2021

World J. Adv. Res. Rev.

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Nodular goiter (NG) is an internationally important health problem. The aim of this exploratory study was to examine the content of silver (Ag), bromine (Br), calcium (Ca), chlorine (Cl), cobalt (Co), chromium (Cr), cooper (Cu), iron (Fe), mercury (Hg), iodine (I), potassium (K), magnesium (Mg), manganese (Mn), sodium (Na), rubidium (Rb), ammonium (Sb), scandium (Sc), selenium (Se), strontium (Sr), and zinc (Zn) in the normal thyroid and in the thyroid tissues with diagnosed colloid NG.. Thyroid tissue levels of twenty chemical elements (ChE) were prospectively evaluated in 46 patients with NG and 105 healthy inhabitants. Measurements were performed using non-destructive energy-dispersive X-Ray fluorescent analysis combined with instrumental neutron activation analysis with high resolution spectrometry of short– and long-lived radionuclides. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for ChE analysis. It was found that during a goitrous transformation the levels of Ag, Br, Cl, Co, Cu, Fe, Hg, Mg, Na, and Sc in thyroid tissue significantly increased, whereas the levels of I and Sr decrease. It was supposed that the changes in levels Ag, Br, Cl, Co, Cu, Fe, Hg, I, Mg, Na, Sc, and Sr in thyroid tissue can be used as NG markers.

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Age-Related Changes of Ag, Co, Cr, Fe, Hg, Rb, Sb,Sc, Se, and Zn Contents in Intact Thyroid of Males Investigated by Neutron Activation Analysis

Cited by 33 publications

References 31 publications

Possible Role of Inadequate Quantities of Intra-Thyroidal Bromine, Calcium and Magnesium in the Etiology of Female Subclinical Hypothyroidism

Possible Role of Inadequate Quantities of Intra-Thyroidal Bromine, Calcium and Magnesium in the Etiology of Female Subclinical Hypothyroidism

Trace Element Contents in Thyroid Cancer Investigated by Energy Dispersive X-Ray Fluorescent Analysis

Determination of twenty chemical element contents in normal and goitrous thyroid using X-ray fluorescent and neutron activation analysis

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