Age-Related Changes of Elements in the Anterior Commissures and the Relationships Among their Elements

Abstract

To elucidate compositional changes of the anterior commissure with aging, the authors investigated age-related changes of elements in the anterior commissures and the relationships among their elements. After ordinary dissection at Nara Medical University was finished, the anterior commissures were resected from 45 subjects, ranging in age from 70 to 101 years. The subjects consisted of 22 men and 23 women. After ashing with nitric acid and perchloric acid, the element content of the anterior commissures was determined by inductively coupled plasma-atomic emission spectrometry. The seven element contents of Ca, P, S, Mg, Zn, Fe, and Na did not change significantly in the anterior commissures with aging. Regarding the relationships among their element contents, significant correlations were found among the contents of Ca, Mg, Zn, and Na in the anterior commissures. The gender difference that the Zn content was significantly higher in men than in women was found in the anterior commissure.

Age-Related Changes of Elements and Relationships Among Elements in Human Hippocampus, Dentate Gyrus, and Fornix

“…The authors previously investigated age-related changes of elements in the corpora callosa [1] and anterior commissures [2] of the white matter and the pineal bodies [3], olfactory bulbs and tracts [4], and mammillary bodies [5] of the gray matter. It was found that a very high accumulation of Ca and P occurred in the pineal body at old age.…”

“…Comparison in Elements with Significant Correlation Among Eight Brain Regions Table 5 indicates elements with significant correlation in the corpus callosum [1], anterior commissure [2], and fornix of the white matter and the pineal body [3], olfactory bulb and [4], mammillary body [5], hippocampus, and dentate gyrus of the gray matter. Significant correlations were found between Ca and P contents, between Ca and Mg contents, between P and Mg contents, and between Ca and Na contents in more than five out of the eight brain regions.…”

Minor and Trace Elements in Cerebrospinal Fluid of Parkinson's Patients – Suggestions After a Critical Review of the Analytical Data

“…In serum, it has been documented for Cu by Ghayour-Mobarhan et al (2005) and Kouremenou-Dona et al (2006); for Se by Lopes et al (2004). In brain, Markesbery et al (1984), Ongkana et al (2010) and Tohno et al (2010)  data converted from nmol/L Table 6. Manganese in Controls and Patients (µg/L) elements.…”

“…For changes of Se, Cu and Zn in serum, see Lopes et al (2004) and Ghayour-Mobarhan et al (2005). For Zn variations in brain, see Ongkana et al (2010). Regarding CSF, Bocca et al (2006) noticed lesser Fe amounts in PD males than in females, whereas the opposite was found in controls.…”

Gender Differences in Elements of Human Anterior Commissure and Olfactory Bulb and Tract

“…To elucidate compositional changes of the brain with aging, the authors previously investigated age-related changes of elements in the corpus callosum [1] and anterior commissure [2] of the white matter and in the pineal body [3], olfactory bulb and tract [4], and mammillary body [5] of the gray matter.…”