Age-related Changes of the Ultrastrucure in the Parathyroid Gland of the Golden Hamster

Abstract

Summary: We qualitatively and quantitatively investigated the parathyroid glands of golden hamsters aged 6, 12, 18, 24 and 30 months. Percent area of rER in the parathyroid gland in golden hamsters at 24 months of age was significantly higher when compared to 6 and 12 months of age, and the percent area at 30 months of age was significantly higher when compared to 12 months of age, but there were no significant differences between 24 and 30 months of age. Percent area of the Golgi apparatus at 24 and 30 months of age was significantly higher when compared to 6, 12 and 18 months of age. Ultrastructurally, we believe that in the parathyroid gland of the golden hamster, synthesis and release of parathyroid hormone increase gradually from 6 to 24months of age and are maintained from 24 to 30 months of age.

Ultrastructural Study of the Age-dependent Effects of the Alendronate Sodium Hydrate Treatment on the Parathyroid Gland in Golden Hamsters

“…The PTG morphology of the control hamsters in each group (Figs. 1 and 2) resembled that of normal hamsters, as reported earlier 3) . Experimental groups.…”

Electron Microscopy and Immunohistochemistry using Indicators of Apoptosis and Proliferation on Guinea Pig Parathyroid Gland

“…Chief cells of Guinea pig contained several secretory granules, small and large similar to mouse, rat and hamster (Isono et al, 1985;Utsumi et al, 2014). However, these results disagreed with rat chief cells contained rare secretory granules as the secretory activity occurs in parathyroid glands of embryonal and fetal rat only (Isono et al, 1990).…”