Age-related features in vestibular migraine onset: A multiparametric analysis

Ori, Michele; Arra, Gabriele; Caricato, M; Freccia, Rocco; Frati, Francesco; Bonis, Teodosio De; Ricci, Giampietro; Faralli, Mario

doi:10.1177/0333102420951505

Cited by 11 publications

(9 citation statements)

References 32 publications

(44 reference statements)

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“…These are the same central neurotransmitters in the processes of anxiety and depression [ 26 ]. Furthermore, among the symptoms indicated in the diagnostic criteria of VM, visually induced vertigo has a significant impact in terms of frequency and symptomatology, even considering the high pleomorphism of this pathology [ 17 , 27 ]. A core of symptoms is common between VM and PPPD.…”

Section: Discussionmentioning

confidence: 99%

Persistent Postural Perceptual Dizziness in Episodic Vestibular Disorders

et al. 2022

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Benign Paroxysmal Positional Vertigo (BPPV), Vestibular Migraine (VM), and Meniere Disease (MD) are among the most common episodic vertigos. Persistent Postural Perceptual Dizziness (PPPD) is a chronic functional vestibular disorder that can arise in patients suffering from one or more of these conditions. We analyzed the role of these vestibular disorders as single or multiple associated comorbidities and as a precipitating condition for PPPD. A total of 376 patients suffering from dizziness with a known history of single or multiple vestibular disorders were preliminarily evaluated. We conducted a careful anamnesis to determine whether the reported dizziness could meet the diagnostic criteria for PPPD. PPPD was diagnosed in 24 cases; its incidence in patients with history of a single comorbidity or multiple vestibular comorbidities was 3.9% and 22.4%, respectively. BPPV, VM, and MD were identified as a precipitating condition in 2.34%, 16.45%, and 3.92%, respectively. BPPV constituted a precipitating condition mainly at the first episode. We observed that the presence of multiple vestibular comorbidities (BPPV, VM, and MD) in patients’ clinical history increased the risk of PPPD. VM plays a significant role in representing a precipitating condition for PPPD, both when present individually or in association with the other vestibular disorders.

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Section: Discussionmentioning

confidence: 99%

Persistent Postural Perceptual Dizziness in Episodic Vestibular Disorders

et al. 2022

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“…In all three of our multiple linear regression models investigating age, sex, and history of psychiatric disorders, VM-PATHI was a statistically significant predictor of daily dizziness severity and superior at capturing daily dizziness than the DHI. Age has been linked with an increased incidence of spontaneous dizziness in vestibular migraineurs (18), and this may explain the reason age was a significant predictor of daily dizziness in two of our models. Despite the female predominance in the VM population and the high comorbidity of psychiatric disorders in individuals who experience dizziness (1,19), neither biological sex nor a history of anxiety/depression predicted daily dizziness.…”

Section: Discussionmentioning

confidence: 78%

Correlating Vestibular Migraine Patient Assessment Tool and Handicap Inventory to Daily Dizziness Symptoms

Kim,

Hum,

Sharon

2023

Otol Neurotol

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Objective Investigate the relationship between Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) scores and daily dizziness symptoms. Study Design Prospective cohort analysis of 52 patients with vestibular migraine (VM). Setting Tertiary referral center. Patients Fifty-two patients diagnosed with VM or probable VM according to Barany Society criteria. Interventions Subjects reported their dizzy symptoms (on a scale of 0 [no symptoms], 1 [mild], 2 [moderate], and 3 [severe]) every day for 1 month via automated text messaging linked to a cloud-based research database. Subjects completed VM-PATHI and Dizziness Handicap Inventory (DHI) scores at the end of the month. We examined the correlation between a composite of daily dizziness scores with VM-PATHI and DHI scores through linear regression and correlation analysis. Main Outcome Measures Pearson correlation coefficient, R 2 value. Results VM-PATHI showed a moderate correlation with daily dizziness symptoms (correlation coefficient, 0.51). DHI showed a lower correlation with daily dizziness (correlation coefficient, 0.38). VM-PATHI score was a strong predictor of daily dizziness with univariate linear regression (R 2 = 0.26, p = 0.001). In a multiple linear regression model with age, history of anxiety and/or depression, and VM-PATHI, the VM-PATHI score was the only statistically significant predictor of daily dizziness (p < 0.001). Conclusions Daily dizziness symptoms are better correlated with VM-PATHI score than the DHI, providing further validation of VM-PATHI as a disease-specific outcome measure for patients with VM.

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“…The type of vestibular symptoms varies according to the age of onset of VM. This conclusion may have been limited by the sample size and the investigators set a temporal cut-off of 60 years old, based on the evidence of the radical decrease in the onset of migraine attacks from the age of 50 ( Ori et al, 2020 ). Furthermore, this study also found that patients with pVM had a higher rate of motion sickness, 72.04%, compared to 51.06% of patients in the cVM group and 23.00% in the control group.…”

Section: Discussionmentioning

confidence: 99%

Study of clinical correlation of motion sickness in patients with vestibular migraine

Meng

Zhou²,

Hu³

et al. 2022

Front. Neurosci.

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ObjectiveIn this study, clinical data from vestibular migraine (VM) patients and healthy control populations were collected to analyze the clinical data of VM patients, especially the history of motion sickness, and to understand their clinical characteristics.MethodsAccording to VM diagnostic criteria, 140 patients diagnosed with confirmed VM (cVM) and probable VM (pVM) who attended the outpatient and inpatient ward of Jiaxing First Hospital between August 2017 and June 2021, as well as 287 healthy check-ups in the health management center, were analyzed and compared in terms of age, gender, and previous history of motion sickness.ResultsA comparison of clinical data related to VM patients and the control population showed that there were more women in the VM group (P < 0.01) and that patients in the VM group were older (P < 0.05) and had a higher prevalence of history of motion sickness history (P < 0.01). Analysis after matching gender and age revealed that patients in the cVM group were older than those in the pVM group (P < 0.05), but the proportion of motion sickness was lower than in the pVM group (P < 0.05). The age of the patients in the cVM group was mainly distributed around 50 years of age, following a normal distribution, whereas the age distribution of the patients in the pVM group did not have a significant trend of age concentration and was distributed at all ages.ConclusionThe history of motion sickness is significant in patients with VM and may be a potential suggestive factor for the diagnosis of VM.

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Age-related features in vestibular migraine onset: A multiparametric analysis

Cited by 11 publications

References 32 publications

Persistent Postural Perceptual Dizziness in Episodic Vestibular Disorders

Persistent Postural Perceptual Dizziness in Episodic Vestibular Disorders

Correlating Vestibular Migraine Patient Assessment Tool and Handicap Inventory to Daily Dizziness Symptoms

Study of clinical correlation of motion sickness in patients with vestibular migraine

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