2008
DOI: 10.1016/j.urology.2007.11.041
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Age-Related Increase of Reactive Oxygen Species in Neat Semen in Healthy Fertile Men

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Cited by 137 publications
(69 citation statements)
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“…The factors responsible for excessive ROS generation by spermatozoa are not entirely clear. Among them, age, environmental, and lifestyle factors are most frequently mentioned in the literature [88][89][90][91]. Interestingly, leukocytospermia has been shown to play a role in stimulating ROS production by the sperm themselves [58,92].…”
Section: Role Of Oxidative Stressmentioning
confidence: 99%
“…The factors responsible for excessive ROS generation by spermatozoa are not entirely clear. Among them, age, environmental, and lifestyle factors are most frequently mentioned in the literature [88][89][90][91]. Interestingly, leukocytospermia has been shown to play a role in stimulating ROS production by the sperm themselves [58,92].…”
Section: Role Of Oxidative Stressmentioning
confidence: 99%
“…A cross-sectional, retrospective study by Rolf et al 43 on 3698 infertile men (mean age: 33 years) identified an age-dependent increase in infections of the accessory sex glands. Given that infections lead to increased oxidative stress and elevated levels of reactive oxygen species have been identified in the spermatozoa of males of APA, 44 it is tempting to speculate that a relationship between oxidative stress, reactive oxygen species and APA exists.…”
Section: Effect Of Paternal Age On Semen Qualitymentioning
confidence: 99%
“…Infections can lead to oxidative stress which can be evaluated by measuring reactive oxygen species (ROS) levels in seminal plasma. ROS levels show a significant, age-dependent increase in the aging male (Cocuzza et al, 2008) and may lead to DNA damage (Aitken and De Iuliis, 2007;Turner and Lysiak, 2008).…”
Section: Paternal Age and Infectionsmentioning
confidence: 99%