Age-Related Macular Degeneration and Quality of Life in Latinos

Choudhury, Farzana; Varma, Rohit; Klein, Ronald; Gauderman, W. James; Azen, Stanley P.; McKean‐Cowdin, Roberta

doi:10.1001/jamaophthalmol.2016.0794

Cited by 25 publications

(26 citation statements)

References 46 publications

(70 reference statements)

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“…40 A recent population-based study conducted in adult Latino population revealed overall NEI-VFQ-25 scores of 59.5 (95% CI, 50.8-68.1) for those with latestage AMD and 79.4 (95% CI, 72.5-86.1) for those with early-stage AMD. 21 The current study showed that patients with similar visual acuity experience similar overall impairment in QoL whether they had early-stage glaucoma or AMD, despite the fact that they essentially affect visual function through different mechanisms. They both experience loss of QoL mainly in subgroups of general health and general vision.…”

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confidence: 52%

“…7,14-21,31-36 They revealed that total scores of general sighted population was significantly higher compared with AMD or POAG patients. 13,14,17,21 Mangione et al 13 observed that overall scores were lower for the patients with various chronic eye diseases including AMD (67.1 ± 13.4) and POAG (80.2 ± 12.5) compared with a reference sample of participants with no evidence of underlying eye disease (88.1 ± 15.3). This suggests that NEI-VFQ-25 is sensitive to different levels of visual function in the better eye of patients with AMD and POAG.…”

Section: Discussionmentioning

confidence: 98%

“…The QoL scores obtained with NEI-VFQ-25 ranged between 69.8 ± 1.9 and 90.7 ± 8.1 for glaucoma patients and between 51.8 ± 2.0 and 79.4 in AMD patients. 4,[14][15][16][17][18][19][20][21] These studies were mainly conducted in advanced forms of these diseases. 4,[14][15][16][17][18] There is little information about vision-specific QoL among patients with early stages of glaucoma and AMD.…”

Section: Introductionmentioning

confidence: 99%

“…4,[14][15][16][17][18] There is little information about vision-specific QoL among patients with early stages of glaucoma and AMD. [19][20][21] There is even less information about the QoL of comparable groups of glaucoma and primary open-angle glaucoma (POAG) patients, and the impact of involvement of different sites, that is, peripheral visual field vs central retina on QoL. The influence of visual disability to perform activities of daily living was generally assessed by tests that evaluated visual acuity and visual field sensitivity.…”

Section: Introductionmentioning

confidence: 99%

“…In patients with advanced POAG and AMD, the reported range of overall NEI-VFQ-25 scores (from 69.8 ± 1.9 to 78.3 ± 14.9 and from 51 ± 2 to 67.8 ± 18, respectively) were lower than the present study (86.44 ± 6.96 and 84.66 ± 7.56, respectively). 4,14,17,18,21,49 Wolfram et al 14 demonstrated that advanced POAG (71.5 ± 19.3) was significantly associated with low NEI-VFQ-25 scores compared with early (90.7 ± 8.1) and moderate POAG (86.1 ± 8.7). Similarly, patients with advanced or late-stage AMD experience a major reduction in QoL.…”

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confidence: 99%

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Comparison of vision-related quality of life in primary open-angle glaucoma and dry-type age-related macular degeneration

Uğurlu

Altundal

Ekin

2016

Eye

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Purpose To compare quality of life (QoL) in patients with primary open-angle glaucoma (POAG) and dry-type age-related macular degeneration (AMD) with similar bestcorrected visual acuity. Methods Age-, sex-, and visual acuitymatched POAG and dry AMD patients were included in the study. Each patient performed 24-2 and 10-2 SITA standard visual field tests. Contrast sensitivity was evaluated with CSV-1000 HGT instrument. The 25 item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) was used to analyze QoL. Overall and subscale scores were converted to scores between 0 and 100, the higher scores indicating better visionrelated QoL. Results Overall NEI-VFQ-25 scores were 86.44 and 84.66 in glaucoma and AMD groups, respectively (P = 0.244). The highest scores were obtained in 'vision-related dependency' subgroup in glaucoma and 'color and peripheral vision' in AMD group, whereas the lowest scores were noted 'in peripheral vision' in both glaucoma and AMD patients. Glaucoma patients had significantly lower scores in ocular pain, color vision, and peripheral vision subgroups compared with the AMD group, whereas AMD patients had lower scores in near and distance vision activities, vision-related social activity, and dependency subgroups. Contrast sensitivity results and mean defect values showed correlation with NEI-VFQ-25 scores in both groups. Conclusions Glaucoma and AMD patients with similar visual acuity experienced similar overall impairment in QoL. However, glaucoma patients described more difficulty with peripheral vision and ocular pain, whereas AMD patients complained more about near and distance vision and dependency items.

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confidence: 52%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Comparison of vision-related quality of life in primary open-angle glaucoma and dry-type age-related macular degeneration

Uğurlu

Altundal

Ekin

2016

Eye

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Cataract Surgery and Age-Related Macular Degeneration in the 2008-2012 Korea National Health and Nutrition Examination Survey

et al. 2016

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In the past, concern has been raised that cataract surgery may be associated with the incidence or progression of age-related macular degeneration (AMD); inconsistent findings from previous studies have puzzled clinicians. In addition, data addressing this association in Asian populations and in the era of phacoemulsification are scarce. OBJECTIVE To determine the associations between cataract surgery and AMD in a representative Korean population. DESIGN, SETTING, AND PARTICIPANTS This cross-sectional study used a multistage, probability-cluster survey sample to produce nationally representative estimates. Data were analyzed from the Korea National Health and Nutrition Examination Survey (KNHANES), which included results for cataract surgery status and AMD grading from 2008 to 2012. A total of 20 419 participants 40 years or older were included. Data were analyzed from February 5 to August 20, 2015. MAIN OUTCOMES AND MEASURES The association between cataract surgery and AMD was assessed in each right and left eye using logistic regression models and in both eyes using generalized estimating equation models. Sample weights were applied to adjust for survey design, nonresponse, and stratification to generate nationally representative population-based results. RESULTS From the 20 419 eligible individuals (11 642 women [51.9%] and 5777 men [48.1%]; mean [SE] age, 55.83 [0.14] years), 17 987 had information regarding cataract surgery status and gradable fundus photographs of at least 1 eye. A total of 34 863 eyes (17 616 right eyes and 17 247 left eyes) underwent analysis. Of these, 1264 right eyes (5.5%) and 1235 left eyes (5.4%) had cataract surgery. Of 1056 right eyes and 949 left eyes with any AMD (early or late), 167 right eyes (15.2%) and 147 left eyes (13.7%) had cataract surgery. The analyses did not show any association between cataract surgery and any form of AMD (early, late, and all) except in left eyes, where cataract surgery was associated with late AMD (odds ratio, 2.34; 95% CI, 1.13-4.85). CONCLUSIONS AND RELEVANCE The results suggest that the association between cataract surgery and AMD is uncertain in the current era of phacoemulsification. The association for left eyes might be a chance finding.

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JAMA Ophthalmology Year in Review, 2016

Bressler¹

2017

JAMA Ophthalmol

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Each year, JAMA Ophthalmology will pause to thank our peer reviewers for their essential contribution to the mission of the journal. The mission of JAMA Ophthalmology is to be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and thereby to be the first choice of authors for their important manuscripts. Embedded within that vision is peer review, 1 of 5 core values of JAMA Ophthalmology, the others being scientific integrity, sensitivity to patient and human subject risks, and a commitment to being ethical and scholarly. However, peer review is the only one that is dependent on experts outside of anyone on the editorial board or anyone else listed on the masthead.Because peer review is voluntary and dependent in part on the altruistic nature of the reviewer, why even have peer reviewers? The answer lies in the process that JAMA Ophthalmology follows to pursue its mission. To publish promptly (currently, median of 57 days from acceptance to publication) (Table ), the senior editors typically review every submission within a week of receipt to determine whether it is likely to meet the priorities of the journal. Those submissions that are judged not to provide substantially new scholarly findings or sufficiently great enough clinical relevance to the general readership of JAMA Ophthalmology based on the objective, methods, and results are rejected (currently, median of 5 days from receipt to rejection). With this approach, the journal is able to tap peer reviewers for their expertise, typically not more than once or twice a year. In that way, the very best peer reviewers are unlikely to perceive an undue burden of numerous reviews while simultaneously receiving articles that have an approximately 50% chance of attaining publication in JAMA Ophthalmology. Occasionally, the peer reviewer's expertise may suggest to the senior editors that there is minimal novelty or that there are shortcomings to the objective, methods, or results that limit the clinical relevance of the investigation, warranting rejection despite peer review. More often, however, the expertise of the peer reviewer provides feedback to the authors that may be incorporated into a revision, which often results in a stronger submission to be reconsidered by the senior editors for possible acceptance and subsequent publication-a win for readers, reviewers, and authors! This approach has led to an unprecedented growth for JAMA Ophthalmology. Not only is the process as fast as any other major ophthalmology journal, but the articles (includ-Opinion EDITORIAL jamaophthalmology.com (Reprinted)

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Age-Related Macular Degeneration and Quality of Life in Latinos

Cited by 25 publications

References 46 publications

Comparison of vision-related quality of life in primary open-angle glaucoma and dry-type age-related macular degeneration

Comparison of vision-related quality of life in primary open-angle glaucoma and dry-type age-related macular degeneration

Cataract Surgery and Age-Related Macular Degeneration in the 2008-2012 Korea National Health and Nutrition Examination Survey

JAMA Ophthalmology Year in Review, 2016

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