1999
DOI: 10.1159/000015905
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Age-Related Transcranial Doppler Findings in the Evaluation of Cerebral Circulation during Postprandial and Postural Tests

Abstract: We used transcranial Doppler (TCD) to investigate whether there are cerebral circulation differences between young and elderly subjects in response to postprandial postural changes. Preprandial and postprandial systolic and diastolic blood pressure, heart rate, mean middle cerebral artery (MCA) velocity (Vmean MCA), systolic/diastolic MCA velocity ratio (Vs/Vd MCA) and pulsatility index (PI) were determined in 15 healthy elderly subjects (mean age 74.3 ± 6.5 years) and in 10 yo… Show more

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Cited by 7 publications
(4 citation statements)
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“…13,14 In this study, cerebrovascular resistance tended to decrease in the group with paraplegia and PPH, but it increased in a previous study, in elderly subjects with PPH.…”
Section: Postprandial Vagal and Sympathetic Responsescontrasting
confidence: 54%
“…13,14 In this study, cerebrovascular resistance tended to decrease in the group with paraplegia and PPH, but it increased in a previous study, in elderly subjects with PPH.…”
Section: Postprandial Vagal and Sympathetic Responsescontrasting
confidence: 54%
“…In the literature, SD of the intraindividual supine to sitting MCA CBFV difference is estimated to be around ±5% for elderly hospitalised patients12 and ±20% for patients with severe stroke going from the 30° to 0° position 9. To detect a difference in mean CBFV of more than 6 cm/s (10–20%) between remaining supine and sitting upright in bed with a probability (power) of 90% when testing at a two-sided significance level of 5%, a sample size of 45 participants was required.…”
Section: Methodsmentioning
confidence: 99%
“…Cerebral hypoperfusion has been implicated as one such mechanism, but progress in this area has been hindered in part by the methodological challenges of measuring cerebral perfusion. Transcranial Doppler (TCD) ultrasound has been used to detect oscillations in global cerebral blood flow [8]. But only mean blood velocity, not blood flow, can be measured with this technique, and it does not analyze blood flow in specific brain regions.…”
Section: Introductionmentioning
confidence: 99%