Age‐specific effect of transurethral holmium laser enucleation of the prostate on overactive bladder in men with benign prostatic hyperplasia: An investigation using an overactive bladder symptom score

Abstract

Objectives: To investigate the age-specific effect of transurethral holmium laser enucleation of the prostate (HoLEP) on overactive bladder (OAB).Methods: A total of 186 consecutive patients who underwent HoLEP were included.They were divided into three groups: patients aged less than 65 years, between 65 and 74, and 75 or older. The OAB symptom score as well as other relevant variables of lower urinary tract symptoms and function were assessed before and 1, 3, 6, and 12 months after surgery. Age-specific prevalence of OAB, the proportion of resolution of OAB, and de novo OAB were evaluated. Results:The mean age of patients was 70.7 years, and the mean total prostate volume was 75.8 ml. The mean OAB symptom scores before surgery of patients aged less than 65 years, between 65 and 74, and 75 or older were 6.0, 5.2, and 5.7, respectively. At 12 months after surgery, the scores for the respective groups had significantly decreased to 2.1, 2.5, and 3.5. The prevalence of OAB based on the

Preoperative factors predicting poor therapeutic efficacy of holmium laser enucleation of the prostate in patients with benign prostatic hyperplasia

“…A previous study reported that between 50% and 75% of patients with BPH exhibited OAB symptoms 23 . Moreover, among patients with preoperative OAB, OAB persisted in more than 20% after HoLEP and approximately 10% required continued postoperative anticholinergic therapy 24,25 . Regarding predictive factors for postoperative medication therapy for OAB symptoms after HoLEP, Kim et al demonstrated that preoperative factors such as a history of OAB, terminal DO, and IPSS urgency items may predict the need for post‐HoLEP medication therapy 26 .…”

“…23 Moreover, among patients with preoperative OAB, OAB persisted in more than 20% after HoLEP and approximately 10% required continued postoperative anticholinergic therapy. 24,25 baseline after HoLEP on the potential need to take anticholinergics in the early postoperative period. 27,28 Therefore, storage symptoms, including urinary urgency, and voiding symptoms need to be examined in the early postoperative period.…”

Choice Of treatment method for symptomatic Bladder outlet obstruction in patients with benign prostatic hyperplasia after kidney transplantation

“…На сегодняшний день широко применяются такие высокотехнологичные методы коррекции СНМП, как трансуретральная энуклеация ПЖ с помощью гольмиевого или тулиевого лазера [66][67][68][69].…”

“…При лазернаой энуклеации иссекают доли предстательной железы вплоть до ее хирургической капсулы, после этого энуклеированные ткани смещают в мочевой пузырь и удаляют [66][67][68][69]. Гольмиевую лазерную энуклеацию (ГЛЭ) применяют при умеренных и выраженных СНМП на фоне объема простаты, превышающего 80 cм 3 [67,68], при этом снижается риск развития кровотечений на фоне антикоагулянтной терапии.…”