Age-Specific Prevalence of Infection with Human Papillomavirus in Females: A Global Review

Smith, Jennifer S.; Melendy, Amy; Rana, Rashida K.; Pimenta, Jeanne M.

doi:10.1016/j.jadohealth.2008.07.009

Cited by 286 publications

(299 citation statements)

References 390 publications

(146 reference statements)

Supporting

Mentioning

228

Contrasting

Unclassified

Order By: Relevance

“…The prevalence of HPV positivity with the HC2 assay (15.7%) in our population is higher than in other settings 32,33 but is similar to that reported in France. 34,35 This can be explained by the fact that our population contained a substantial proportion (25%) of young women.…”

Section: Discussionsupporting

confidence: 84%

“…The HC2 DNA assay is based on qualitative detection of L1 in 13 HR-HPV types (16,18,31,33,35,39,45, 51, 52, 56, 58, 59 and 68). 20,26 Specimens for HC2 testing were collected in LBC/ThinPrep and transported to the central laboratory at 2-30 C. Specimens were tested according to the manufacturer's instructions.…”

Section: Hpv Testingmentioning

confidence: 99%

“…The AHPV RNA assay is based on the qualitative detection of E6/E7 viral mRNA of 14 HR-HPV genotypes (16,18,31,33,35,39,45, 51, 52, 56, 58, 59, 66 and 68) from cervical specimens collected into ThinPrep LBC vials. 27 AHPV utilizes the technologies of target capture, transcriptionmediated amplification and dual kinetic assay.…”

Section: Hpv Testingmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid‐based cytology in primary cervical cancer screening: The FASE study

Monsonégo

Hudgens

Zerat³

et al. 2010

Intl Journal of Cancer

Self Cite

132

View full text Add to dashboard Cite

The APTIMA V R HPV Assay (AHPV) allows detection of 14 high-risk human papillomavirus (HPV) RNA types in cervical specimens. Until present, the assay has been compared to HPV DNA tests only in triage settings. Herein, we compare AHPV with a DNA assay (Hybrid Capture V R 2; HC2) and liquid-based cytology (LBC; using PreservCyt V R ThinPrep liquid Pap) in a screening setting (French APTIMA screening evaluation [FASE] study). Women (N 5 5,006) aged 20-65 were screened by gynecologists in 17 private practices in Paris, France. One cervical specimen was collected and tested with LBC, AHPV and HC2 assays. Women were referred to colposcopy if they were ASC-US1 in LBC or HPV positive in either HPV assay. To control for verification bias, a random group (14%) with normal LBC and dually HPV negative tests underwent colposcopy. Data from 4,429 women were analyzed. Sensitivity, specificity and predictive values were calculated for the three tests. AHPV and HC2 were highly sensitive for CIN21 (92.0% and 96.7%) and CIN31 (95.7% and 95.3%) detection and much more sensitive than LBC (69.1% for CIN21 and 73.3% for CIN31). Specificity of AHPV was higher than that of HC2, but similar to that of LBC (p < 0.001). Combining LBC with either HPV test slightly increased sensitivity but compromised specificity. AHPV assay is both specific and sensitive for the detection of high-grade precancerous lesions and may be considered as an option for routine cervical cancer screening for women over 20 years of age.Invasive cervical cancer (ICC) is the second most frequent female cancer worldwide, 1 with an estimation of 493,000 cases annually. ICC incidence and mortality rates have dramatically declined over the past five decades in developed countries, largely due to screening programs based on conventional cervical Papanicolaou (Pap) smears. 2,3 Conventional Pap smear screening, however, has limited sensitivity, positive predictive value (PPV) and reproducibility, which limits its use for primary screening. 3,4-7 Liquid-based cytology (LBC) has been shown to be more sensitive than conventional

show abstract

Section: Discussionsupporting

confidence: 84%

Section: Hpv Testingmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid‐based cytology in primary cervical cancer screening: The FASE study

Monsonégo

Hudgens

Zerat³

et al. 2010

Intl Journal of Cancer

Self Cite

132

View full text Add to dashboard Cite

show abstract

“…Also low-risk HPV types (type 6 and 11) appear as genital warts in both males and females leading to low quality of life (Lacey et al, 2006). Young women especially at the age of college are the most prone group to this STD, because of high trend to have sexual activity with different partners (Ho et al, 1998;Smith et al, 2008;D'Souza et al, 2012). In a study conducted in Malaysia, results showed an increasing rate of STD among the young comparing to old women (Ramachandran and Ngeow, 1990).…”

Section: Discussionmentioning

confidence: 99%

Parental Knowledge and Attitudes about Human Papilloma Virus in Iran

Ghojazadeh¹,

Naghavi-Behzad²,

Azar³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Infection by human papillomavirus (HPV) is one of common sexually transmitted diseases leading to cervical cancer. Evaluation of parental knowledge and attitudes toward HPV were aims of present study to provide an appropriate method to decrease burden of this infection on society. During this study, 358 parents were assessed for knowledge about HPV and its related disorders. Some 76% of parents had no information about HPV infection and among the informed parents 36% had obtained their information via internet and others from studying medical resources. The average score of mothers information about HPV infection was higher than that of fathers, and also educational level and age had significant impact on knowledge of parents about HPV. Parent knowledge about the hazards of HPV was higher than their knowledge about modes of transmission. Lack of awareness about HPV infection was high in this study, underlining the urgency of education among all adult people in our society.

show abstract

“…HPV is spreading through sexual contact; Studies point out that 30-60% of all sexually active adults acquire HPV during their reproductive lives (Tindle, 2002) and it is suspected to be higher in younger women comparing to older women (Smith et al, 2008). Fortunately more than 80% of HPV infections are removed over a 3-4 years without any intervention; on the other hand primary prevention trough vaccination and screening for cervical cancer seems to be effective (Wong, 2009).…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Attitude of Iranian University Students toward Human Papilloma Virus

Ghojazadeh

Azar²,

Saleh³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Introduction: Increasing prevalence of human papilloma virus (HPV) infection and its association with cervical cancer as a leading cause of death make it necessary to evaluate and improve the public knowledge, especially of university students, about this cause of disease. Methods: A cross-sectional study of knowledge and attitude of a total 669 students from Tabriz University of Medical Sciences was therefore performed with a modified validated questionnaire, arranged into 5 parts and containing 55 questions, in July 2011. Questions were directed to study socio-demographic characteristics of the participant, knowledge about HPV disease, transmission route, relationship with cervical cancer, predisposing factors, and participants attitude toward people with HPV infection. Results: All of the participants were Moslem with a mean age 25.6±5.33 years of age. All of the participants had heard of HPV, and acquired their knowledge through university courses (90.6%); the majority of them knew that HPV is a sexually transmitted disease and a potential cause for genital warts but general knowledge about details was not high. Mean knowledge score of residents and post graduate midwifery and nursing students was high as compared to other groups (P<0.001). Statements that indicated the presence of fear to communicate with people suffering HPV and people's avoidance to rely on babysitting of these patients were observed. Educational level (β=0.21, P<0.001), age (β=0.18, P=0.002,) and smoking (β=-0.11, P=0.006) were predicted to effect knowledge. Conclusions: Moderate level of knowledge about HPV among medical university students makes it necessary to set effective national public health efforts on HPV education and prevention considering he excess of young population in Iran vulnerable to cervical cancer.

show abstract

Age-Specific Prevalence of Infection with Human Papillomavirus in Females: A Global Review

Cited by 286 publications

References 390 publications

Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid‐based cytology in primary cervical cancer screening: The FASE study

Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid‐based cytology in primary cervical cancer screening: The FASE study

Parental Knowledge and Attitudes about Human Papilloma Virus in Iran

Knowledge and Attitude of Iranian University Students toward Human Papilloma Virus

Contact Info

Product

Resources

About