Age‐specific risk of fetal loss post second trimester amniocentesis: analysis of 5043 cases

Mazza, Vincenzo; Pati, M.; Bertucci, Emma; Re, Claudia; Ranzi, Andrea; Percesepe, Antonio; Forabosco, Antonino; Volpe, Annibale

doi:10.1002/pd.1647

Cited by 86 publications

(19 citation statements)

References 23 publications

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“…The risk for Brought to you by | University of Iowa Libraries Authenticated Download Date | 6/3/15 11:30 AM fetal loss was no different among the operators, because all five were experienced. These results are in accordance with the published data of previous studies [9,[21][22][23][24].…”

Section: Discussionsupporting

confidence: 96%

Risk for fetal loss and prematurity after 12,413 second trimester amniocenteses in a single center

Theodora

Antsaklis

Blanas

et al. 2015

Journal of Perinatal Medicine

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Section: Discussionsupporting

confidence: 96%

Risk for fetal loss and prematurity after 12,413 second trimester amniocenteses in a single center

Theodora

Antsaklis

Blanas

et al. 2015

Journal of Perinatal Medicine

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“…12 Chorionic villus sampling procedure-related loss rates are similar to amniocentesis when performed in experienced centers. 13 If a false-negative result occurs, some may say that the families who had undergone testing are no worse off for having a screening test for a rare condition.…”

Section: Financial Disclosurementioning

confidence: 75%

Noninvasive Prenatal Testing for Microdeletion Syndromes and Expanded Trisomies

Vora

O’Brien

2014

Obstetrics &Amp; Gynecology

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The identification of circulating cell-free fetal DNA in maternal plasma has led to the introduction of noninvasive prenatal tests with high sensitivity and high specificity for common aneuploidies (trisomy 13, trisomy 18, trisomy 21). A new expanded noninvasive prenatal testing panel that includes five microdeletion syndromes (22q11 deletion syndrome, cri-du-chat [5p minus], Prader Willi or Angelman syndrome, 1p36 deletion syndrome) and two aneuploidies usually associated with nonviable pregnancies (trisomy 16 and trisomy 22) is now available. This expanded panel will be performed unless an opt-out box is checked. Because these disorders are so rare, the positive predictive value is expected to be low. As with all new screening tests and technologies, the expanded panel should be appropriately studied before it is widely adopted.

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“…15,27 In the same way maternal age and abnormal maternal serum a fetoprotein measurements increase the risk for pregnancy loss. 19,[28][29][30][31] Vaginal bleeding during current pregnancy increase the risk of spontaneous abortion and pregnancy loss after amniocentesis in most of the series. 29 In our recent series, we also found that bleeding during first and early second trimester of current pregnancy increase the risk of pregnancy loss after amniocentesis by two to three times.…”

Section: 10 Fetal Lossmentioning

confidence: 99%