Abstract-Large-scale hypertension screening campaigns have been recommended for middle-income countries. We sought to identify sociodemographic predictors of hypertension prevalence, diagnosis, treatment, and control among middleincome countries. We analyzed data from 47 443 adults in all 6 middle-income countries (China, Ghana, India, Mexico, Russia, and South Africa) sampled in nationally representative household assessments from 2007 to 2010 as part of the World Health Organization Study on Global Aging and Adult Health. We estimated regression models accounting for age, sex, urban/rural location, nutrition, and obesity, as well as hypothesized covariates of healthcare access, such as income and insurance. Hypertension prevalence varied from 23% (India) to 52% (Russia), with between 30% (Russia) and 83% (Ghana) of hypertensives undiagnosed before the survey and between 35% (Russia) and 87% (Ghana) untreated. Although the risk of hypertension significantly increased with age (odds ratio, 4.6; 95% confidence interval, 3.0-7.1; among aged, 60-79 versus <40 years), the risk of being undiagnosed or untreated fell significantly with age. Obesity was a significant correlate to hypertension (odds ratio, 3.7; 95% confidence interval, 2.1-6.8 for obese versus normal weight), and was prevalent even among the lowest income quintile (13% obesity). Insurance status and income also emerged as significant correlates to diagnosis and treatment probability, respectively. More than 90% of hypertension cases were uncontrolled, with men having 3 times the odds as women of being uncontrolled. Overall, the social epidemiology of hypertension in middle-income countries seems to be correlated to increasing obesity prevalence, and hypertension control rates are
Basu and Millett
HTN in Middle-Income Countries 19(SAGE), which assembled nationally representative cohorts from 6 countries undergoing rapid economic development (China, Ghana, India, Mexico, Russia, and South Africa). 20 A major advantage of the study was that, as opposed to singlecountry surveys, the SAGE questionnaires and methods were validated and applied simultaneously to multiple countries, investigating what factors may be common and generalizable between nations rather than specific to certain cultures (eg, because of local nutrition), unobserved genetic differences, or healthcare system differences.
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MethodsWe conducted an analysis of the SAGE data set, including participants aged ≥18 years who were surveyed between 2007 and 2010 (Wave 1, used to study health status and social/epidemiological risk factors to poor health) from households within China, Ghana, India, Mexico, Russia, and South Africa. The SAGE clustered household sampling strategy was designed to generate nationally representative cohorts. We excluded pregnant respondents and those that did not have complete blood pressure data or hypertension diagnostic and treatment history on interview. Table 1 describes the demographic make-up and sample sizes in the study.
Blood Pressure MeasurementsBlood pressur...