Ageing and autobiographical memory for emotional and neutral events

Jacques, Peggy L. St.; Levine, Brian

doi:10.1080/09658210601119762

Cited by 177 publications

(146 citation statements)

References 62 publications

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“…In older adults, AM for personal events is typically more gist-like, lacks details (Addis, Wong, & Schacter, 2008;St-Jacques & Levine, 2007;Levine, Svoboda, Hay, Winocur, & Moscovitch, 2002), and is less vivid (Piolino et al, 2006). Only two studies have compared the neural correlates of AM in young and older adults.…”

Section: Introductionmentioning

confidence: 99%

Influence of Aging on the Neural Correlates of Autobiographical, Episodic, and Semantic Memory Retrieval

St-Laurent

Abdi

Burianová

et al. 2011

Journal of Cognitive Neuroscience

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Abstract■ We used fMRI to assess the neural correlates of autobiographical, semantic, and episodic memory retrieval in healthy young and older adults. Participants were tested with an eventrelated paradigm in which retrieval demand was the only factor varying between trials. A spatio-temporal partial least square analysis was conducted to identify the main patterns of activity characterizing the groups across conditions. We identified brain regions activated by all three memory conditions relative to a control condition. This pattern was expressed equally in both age groups and replicated previous findings obtained in a separate group of younger adults. We also identified regions whose activity differentiated among the different memory conditions. These patterns of differentiation were expressed less strongly in the older adults than in the young adults, a finding that was further confirmed by a barycentric discriminant analysis. This analysis showed an age-related dedifferentiation in autobiographical and episodic memory tasks but not in the semantic memory task or the control condition. These findings suggest that the activation of a common memory retrieval network is maintained with age, whereas the specific aspects of brain activity that differ with memory content are more vulnerable and less selectively engaged in older adults. Our results provide a potential neural mechanism for the well-known age differences in episodic/autobiographical memory, and preserved semantic memory, observed when older adults are compared with younger adults. ■

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Section: Introductionmentioning

confidence: 99%

Influence of Aging on the Neural Correlates of Autobiographical, Episodic, and Semantic Memory Retrieval

St-Laurent

Abdi

Burianová

et al. 2011

Journal of Cognitive Neuroscience

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“…In addition, older adults retrieve autobiographical memories with fewer event-specific details than those reported by younger adults (Addis et al, 2008;Levine et al, 2002;Piefke and Fink, 2005; St Jacques and Levine, 2007). For these reasons, a full understanding of the impact of aging on the neural mechanisms underlying memory requires an assessment of the brain circuits at play when memory fails.…”

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confidence: 99%

Age differences in brain activity related to unsuccessful declarative memory retrieval

2015

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Although memory recall is known to be reduced with normal aging, little is known about the patterns of brain activity that accompany these recall failures. By assessing faulty memory, we can identify the brain regions engaged during retrieval attempts in the absence of successful memory and determine the impact of aging on this functional activity. We used functional magnetic resonance imaging to examine age differences in brain activity associated with memory failure in three memory retrieval tasks: autobiographical (AM), episodic (EM) and semantic (SM). Compared to successful memory retrieval, both age groups showed more activity when they failed to recall a memory in regions consistent with the salience network (SLN), a brain network also associated with non-memory errors. Both groups also showed strong functional coupling among SLN regions during incorrect trials and in intrinsic patterns of functional connectivity. In comparison to young adults, older adults demonstrated (1) less activity within the SLN during unsuccessful AM trials; (2) weaker intrinsic functional connectivity between SLN nodes and dorsolateral prefrontal cortex; and (3) less differentiation of SLN functional connectivity during incorrect trials across memory conditions. These results suggest that the SLN is engaged during recall failures, as it is for non-memory errors, which may be because errors in general have particular salience for adapting behavior. In older adults, the dedifferentiation of functional connectivity within the SLN across memory conditions and the reduction of functional coupling between it and prefrontal cortex may indicate poorer internetwork communication and less flexible use of cognitive control processes, either while retrieval is attempted or when monitoring takes place after retrieval has failed. Keywords fMRI; aging; episodic memory; salience network; frontal lobe IntroductionA number of studies have provided extensive evidence of the neural circuitry that supports memory retrieval (e.g., Cabeza and Nyberg, 2000;Spaniol et al., 2009 CIHR Author Manuscript CIHR Author Manuscript CIHR Author Manuscript2008), as well as evidence of how aging influences this circuitry (e.g., Cabeza et al., 2005;Grady, 2012;Rajah and D'Esposito, 2005). However, most research has investigated how the brain supports successful memory performance (Addis and McAndrews, 2006;Brewer et al., 1998;Morcom et al., 2003;Wagner et al., 1998), and limited attention has been paid to brain networks involved in faulty memory retrieval, most notably faulty long-term memory recall. A number of processes may be engaged during recall, including goal setting, memory search, accessing (hopefully correct) stored memories, and evaluating retrieval success (Henson et al., 1999;Moscovitch, 1992;Rugg et al., 2002). The assessment of faulty memory retrieval can be used to identify brain regions whose activity reflects processes engaged when retrieval fails. Such processes can include cognitive control processes involved regardless of retrieval succes...

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“…With regard to autobiographical memory, research reveals that there is deterioration in the episodic part of autobiographical memory in standard aging. Most studies have compared young subjects (about 35 years old) to older subjects [34,[43][44][45][46][47], but other studies have reported a progressive decline in episodic autobiographical memory, comparing healthy subjects aged 50-100 [35,36,45,48,49]. However, the fact that the loss of episodic details leads to a greater production of semantic memories can be interpreted as a process of "semantization" of autobiographical memory.…”

Section: Autobiographical Memory During Agingmentioning

confidence: 99%

Behavior and Emotion in Dementia

Rodríguez¹,

Sales²,

RedondoFlores³

et al. 2016

Update on Dementia

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During the course of disease, the patient and caregiver face emotional and behavioral problems that may occur. Therefore, it is important to knowing how emotions and the perception of them are modified and thus to know the impact they have on mood and behavior of the patient and caregiver. Publicizing the type of pathology, both emotional and behavioral levels, in a patient with dementia can help in the development of nonpharmacological interventions that could slow the symptoms and improve the quality of life of patients.

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Ageing and autobiographical memory for emotional and neutral events

Cited by 177 publications

References 62 publications

Influence of Aging on the Neural Correlates of Autobiographical, Episodic, and Semantic Memory Retrieval

Influence of Aging on the Neural Correlates of Autobiographical, Episodic, and Semantic Memory Retrieval

Age differences in brain activity related to unsuccessful declarative memory retrieval

Behavior and Emotion in Dementia

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