Agenesis and lipoma of corpus callosum: Case report

Abstract

SUMMARY -The agenesis and lipoma of the corpus callosum is a very rare association. We report the case of a 18-years old woman with rare epileptic seizures since the age of 6 years, normal neurological examination, as well as normal electroencephalogram. The brain computed tomography scanning and the magnetic resonance showed the lipoma and the agenesis of the corpus callosum.KEY WORDS: corpus callosum, lipoma, agenesis. Agenesia e lipoma de corpo caloso: relato de casoRESUMO -A agenesia e lipoma do corpo caloso é uma associação muito rara. Relatamos o caso de uma paciente de 18 anos com raras crises epilépticas desde os 6 anos de idade, exame neurológico normal, assim como eletrencefalograma normal. A tomografia computadorizada de crânio e a ressonância magnética mostraram o lipoma e a agenesia de corpo caloso.PALAVRAS CHAVES: corpo caloso, lipoma, agenesia. Corpus callosal lipoma (CCL) is REPORT OF CASEJR, a 18-year-old woman was referred for investigation of epileptic seizures. She had a history of tonicclonic generalized seizures since 6 years of age. Their seizures lasts no longer than a few minutes, occurred up to 4 per year, mainly during the sleep and complaint of headache as the only postictal change. Pregnancy and delivery were normal, as was the child's early development. The antenatal history had been unremarkable. Physical and neurological examination were normal. Phenobarbital monotherapy was started with 100 mg/day. A conventional EEG performed for 30 min was normal during the awake and sleep state. CT as well as the MR showed the lipoma and the agenesis of CC. The CT scans were characterized by regular low density image filling the place of the CC (lipoma) an bordered on each side by two shell-like calcifications. The MR was carried out with Tl and T2 weighted images and showed the following findings: (a) indirect signs of callosal *Head of the EEG Sector, Escola Paulista de Medicina (EPM);

Midline Developmental Anomalies With Lipomas in the Corpus Callosum Region

“…Epilepsy in callosal lipoma is severe, nearly always partial, and begins before the age of 15 years. 17,18 Sometimes lipoma can cause internal hydrocephalus by cerebrospinal fluid pathway obstruction. 19 Cerebral angiography reveals dysplastic, irregulary dilated anterior cerebral arteries.2° CT demonstrates a low-density mass with peripheral calcification between the frontal horns and above the anterior third ventricle.…”

Lipoma de corpo caloso: relato de caso

“…1 Vonderahe e Niemer descreveram uma ocorrência de 0,08% após analise de 5000 autópsias de LCC, e uma rara associação com agenesia. 2 A porção anterior do corpo caloso é o principal sitio de localização topográfica. 3 A formação embriogênica do corpo caloso dá-se no sentido anterior para posterior, exceto a porção rostral.…”