Agenesis of the ductus venosus associated with direct umbilical venous return into the heart—case series and review of literature

Sau, Ashis; Sharland, Gurleen; Simpson, John

doi:10.1002/pd.882

Cited by 57 publications

(73 citation statements)

References 26 publications

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“…The absence of DV is most often reported by prenatal ultrasound. [2][3][4][5][6][7][8][9][10] We found only one previous case report of umbilical venous catheter placement in an infant with an absent DV. 11 In this previously reported case, there was one umbilical artery and two umbilical veins and the umbilical vein followed a similar path as in our case into the iliac vein.…”

Section: Discussionmentioning

confidence: 99%

Congenital absence of ductus venosus: an umbilical catheter with an abnormal path

2009

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Section: Discussionmentioning

confidence: 99%

Congenital absence of ductus venosus: an umbilical catheter with an abnormal path

2009

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“…This might be due to volume overload because of loss of regulatory mechanism by ductus venosus. 3,7,8,9,10 Single umbilical artery has not shown any co-relation with absent ductus venosus in the literature; however multiple aneuplodies have been reported. 11 Here we are presenting a case of absent ductus venosus with single umbilical artery which is extremely rare and other anomalies in form of mal-aligned spine, hydronephrotic kidneys.…”

Section: Discussionmentioning

confidence: 99%

Absent Ductus Venosus With Single Umbilical Artery: A Rare Association

Netam¹,

Kumar²,

Gupta³

et al. 2015

jemds

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Absent ductus venosus is a rare anomalous venous connection in fetus where the fetal outcome depends on type of venous connection and associated anomalies. Poor outcome is reported where the umbilical vein directly drains in to Rt atrium bypassing liver. Better resolution of ultrasound with Color Doppler makes possible to detect the anomaly early. Here we are presenting a case of antenataly diagnosed absent ductus venous with umbilical vein directly draining in to Rt atrium bypassing liver. Case was diagnosed by Ultrasonography with color Doppler and MRI study. INTRODUCTION:Normally in fetal circulation Oxygen-rich blood is carried by the umbilical vein from the placenta to the fetus. The umbilical vein enters at the umbilicus and gives two branches: right umbilical vein passing to the right side of the liver, is joined by the portal vein, and finally drains into the inferior vena cava (IVC) via the hepatic veins. The left umbilical vein gets shunted via the ductus venosus into the IVC bypassing the hepatic circulation and shunting the oxygenated blood primarily to fetal brain and myocardium. Due to such a critical role ductus venosus has an upper hand in conjunction to other fetal shunts. Here we present a case of absent ductus venosus with single umbilical artery and other associated anomalies which was diagnosed during routine ultrasound examination and subsequently examined by 3 Tesla MRI.

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“…Bunlardan biri de DV agenezisidir. 3,4 DV yokluğunda, umbilikal ven venöz sisteme iki farklı şekilde drene olabilir. İlki, karaciğeri baypas ederek sistemik venöz dolaşıma başka bir venöz kanal üzerinden ekstrahepatik yolla; ikinci olarak portal venöz sistem aracılığı ile intrahepatik yolla drene olur.…”

Section: Olgu Sunumuunclassified

“…5 DV agenezisi kardiyak (atriyal septal defekt, ventriküler septal defekt, kompleks kardiyak anomaliler), gastrointestinal (duodenal atrezi, anal atrezi, anüler pankreas, trakeoözofageal fistül), genitoüriner (bilateral hidronefroz, ektopik böbrek, unilateral renal agenezi, hipospadias), kas ve iskelet sistemi anomalilerine (hemivertebra, mezomeli) ve kromozomal anomalilere (Turner sendromu, Noonan sendromu, Trizomi 22) eşlik edebilmektedir. 4 Dolayısıyla fetal anatominin detaylı incelenmesi ve karyotip analizi gereklidir. Olgumuzda karyotip normal olmasına karşın, literatürle benzer biçimde, eşlik eden gastrointestinal anomali (özofagus atrezisi), iskelet sistemi anomalisi (postnatal tanısı konan hemivertebra) ve tek umbilikal arter gibi ek yapısal anomaliler izlendi.…”

Section: Olgu Sunumuunclassified

“…Olgumuzda karyotip normal olmasına karşın, literatürle benzer biçimde, eşlik eden gastrointestinal anomali (özofagus atrezisi), iskelet sistemi anomalisi (postnatal tanısı konan hemivertebra) ve tek umbilikal arter gibi ek yapısal anomaliler izlendi. [3][4][5] DV agenezisinde prognozu belirleyen en önemli faktörlerden biri de, eşlik eden anomalilere ek olarak umbilikal venin drenaj şekli ve portal sistemin ne kadar geliştiğidir. Umbilikal venin karaciğeri baypas ederek direkt olarak sağ atriyuma, inferior vena kavaya veya dallarına açıldığı durumlarda kalbin yükünün arttığı, preload artışına bağlı olarak miyokardiyal ihtiyacın da artarak kalp yetmezliği (kardiyomegali, triküspi yetmezliği, hidrops) gelişebildiği öne sürülmüştür.…”

Section: Olgu Sunumuunclassified

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Congenital Ductus Venosus Agenesis in a Fetus with Dilated Umbilical Vein and Inferior Vena Cava: Case Report

Erzincan¹,

Sayın²,

İnan³

et al. 2016

Turkiye Klinikleri J Gynecol Obst

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Fetal dolaşım sistemi, mevcut olan üç şant nedenile erişkin dolaşım sisteminden farklılık göstermektedir. Bu şantlar duktus venozus (DV), foramen ovale, duktus arterirozus'tur. Fetal gelişim sürecinde başlan-gıçta bulunan sağ ve sol umbilikal venlerden sağdaki regrese olurken, sol umbilikal venin abdomene giriş yeri ile inferior vena kava arasındaki kısmı sebat ederek DV'yi oluşturmaktadır. Plasentadan umbilikal ven aracılığıyla dönen kanın yaklaşık %25 -30'luk kısmı DV yoluyla direktinferior vena kavaya dökülerek sağ atriyuma, buradan da foramen ovale yoluyla sol kalbe ve sistemik dolaşıma ulaşmaktadır. 59Dilate Umbilikal Ven ve İnferior Vena Kava İzlenen Fetüste Konjenital Duktus Venozus Agenezisi Ö ÖZ ZE ET T Duktus venozus (DV) agenezisi, nadir görülen bir vasküler anomalidir. Bu olgu çalışmadada, gastrointestinal ve iskelet sistemi anomalilerine eşlik eden DV agenezisini sunulmuştur. Polihidramniyor nedenile refere edilen olguda yapılan ultrasonografik değerlendirmede, polihidramniyoz yanı sıra özofagus atrezisi ve tek umbilikal arter saptandı. DV'in olmadığı ve umbilikal venin diret inferior vena kavaya drene olduğu izlendi. Preterm doğan yenidoğanda postnatal dönemde hemivertebra da saptandı ve karyotip sonucu normal olarak raporlandı. Postpartum dönemde kardiyovasküler komplikasyon gelişmeyen olgu bronkopulmoner displazi nedenile 71. gün kaybedildi. DV agenezisi, prenatal taramada dikkat edilmesi gereken önemli bir durumdur. Umbilikal venin ekstrahepatik yolla inferior vena kavaya drene olduğu tip DV agenezilerinde prognoz beklentisi özel-likle eşlik eden diğer anomalilere göre daha kötüdür.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Umblikal venler; prenatal tanı; anormallikler A AB BS S T TR RA AC CT T Agenesis of ductus venosus (DV) is a rare vascular abnormality. Here, we report a case of DV agenesis associated with gastrointestinal and skeletal system abnormalities. The patient was referred due to polyhydramnios, and on ultrasonographic evaluation besides polyhydramnios, esophageal atresia and single umbilical artery were also found. DV was not detected and it was observed that umbilical vein drained directly to the inferior vena cava. Hemivertebra and normal karyotype were also detected postnatally in the newborn who was delivered prematurely. Although the baby did not develop any cardiovascular complications the baby died because of bronchopulmonary dysplasia on postpartum 71 st day. Agenesis of DV is an important issue that should be paid attention in prenatal screening. The prognosis is worse in patients with agenesis of DV in which umbilical vein drains directly to inferior vena cava via extrahepatic way especially due to associated anomalies. K Ke ey y W Wo or rd ds s: : Umbilical veins; prenatal diagnosis; abnormalities T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i J J G Gy yn ne ec co ol l O

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Agenesis of the ductus venosus associated with direct umbilical venous return into the heart—case series and review of literature

Cited by 57 publications

References 26 publications

Congenital absence of ductus venosus: an umbilical catheter with an abnormal path

Congenital absence of ductus venosus: an umbilical catheter with an abnormal path

Absent Ductus Venosus With Single Umbilical Artery: A Rare Association

Congenital Ductus Venosus Agenesis in a Fetus with Dilated Umbilical Vein and Inferior Vena Cava: Case Report

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