Agenesis of the ductus venosus – an irrelevant anomaly or a severe clinical problem?

Cnota, Wojciech; Włoch, Agata; Czuba, Bartosz; Wójtowicz, Dominika; Sodowski, Krzysztof

doi:10.17772/gp/1623

Cited by 2 publications

(1 citation statement)

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“…This variant may result in reduced perfusion and oxygenation of the liver, cardiomegaly, congestive heart failure, and intrauterine fetal death. 1,6,[10][11][12][13] We have presented cases with extrahepatic shunts of the UV to the IVC. The 5 cases with additional anatomic and chromosomal anomalies terminated pregnancies before intrauterine fetal death could occur.…”

Section: Discussionmentioning

confidence: 99%

Umbilical Vein Insertion into the Inferior Vena Cava

Weissmann-Brenner

Zalel

2014

J of Ultrasound Medicine

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This series describes the sonographic characteristics and pregnancy outcomes of fetuses with abnormal insertion of the umbilical vein (UV) into the inferior vena cava (IVC). We conducted a retrospective study that described the sonographic features of 6 patients who underwent a routine anatomic scan during early pregnancy. Six patients had a diagnosis of abnormal insertion of the UV to the IVC; in 3, the diagnosis was made at 12 weeks' gestation. Cardiac anomalies were detected in 3 patients, including ventricular septal defects, pericardial effusion, tricuspid and mitral regurgitation, and an aberrant right subclavian artery. Four had noncardiac anomalies, including cystic hygroma and skeletal, brain, and abdominal anomalies. Only 1 fetus who presented with UV insertion into the IVC as an isolated finding had a normal karyotype, resulting in term vaginal delivery. Four other patients had chromosomal abnormalities, including trisomies 13 and 21, Turner mosaicism of 45,XO/46,XY, and Robertsonian translocation, and 1 patient terminated the pregnancy without a karyotype evaluation. Abnormal insertion of the UV into the IVC with agenesis of the ductus venosus can be seen as early as the first trimester. When detected, a detailed anatomic examination should be performed, as well as a fetal karyotype evaluation. Isolated cases of insertion of the UV into the IVC at a position lower than usual may have a good prognosis.

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