Background: Non-steroidal anti-inflammatory (NSAI) drugs are widely used for their analgesic, antipyretic and antiinflammatory effects. The aim of this study is to evaluate the prescribing trends of NSAI drugs among the doctors working the outpatients clinics in our hospital. Materials and methods: Questionnaires consisting of 10 questions related to analgesic and NSAI drug preferences were applied to the doctors working the medical and surgery outpatient clinics in a tertiary care hospital in the Middle Anatolia, and data was collected. Results: The frequency of prescription of NSAI drug in our hospital were found 34,5%. In the internal and surgical departments, respectively, most often diclofenac (23.1%) and dexketoprofen (43.5%) were being prescribed. The most frequent cause of prescribing was joint pain (57,7%) in the internal departments and postoperative pain (73,9%) in the surgical departments. Conclusion: Unnecessary use of NSAI drugs should be avoided because of the high side effect risk despite it's efficacy and benefits and our knowledge of these drugs we prescribe frequently must be updated.