Aggregation of red cells and linear velocity gradients: influence on the correlation-based method for quantitative IVUS blood flow at 20 MHz

Lupotti, F.A.; Zimmer, Audrey; Daronat, Michel; Foster, F. Stuart; Steen, Antonius F.W. van der; Cloutier, Guy

doi:10.1109/ultsym.2002.1192588

Cited by 2 publications

(1 citation statement)

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“…[1][2][3] When in serted into an ar tery or vein, [3][4][5] blood gen er ally flows per pen dic u lar to the im age plane, which makes Dopp ler tech niques im prac ti cal. Frame-to-frame cor re la tion 4,[6][7][8][9][10][11] and decorrelation [12][13][14][15][16][17][18][19][20][21] tech niques have been pro posed and used to ob tain quan ti ta tive blood flow mea sure ments. 13 The main draw back of cor re la tion tech niques is the com pu ta tional cost and lack of real-time func tion al ity un less very ex pen sive, ded i cated hard ware is used.…”

Section: Introductionmentioning

confidence: 99%

Blood Flow Estimation Error with Intravascular Ultrasound Due to In-Plane Component of Flow

Ana

O’Donnell

2003

Ultrason Imaging

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Previously, we presented a real-time method to measure blood flow perpendicular to the image plane of an intravascular ultrasound (IVUS) imaging system using a slow-time FIR (finite impulse response) filter bank. Any in-plane flow introduces error in the flow measurement using the filter bank algorithm. Simulations show that for a flow angle of +/- 10 degrees and velocities between 200 mm/s and 300 mm/s, the energy within the lowest frequency band filter is 6.92 to 7.80 times higher than for perpendicular flow in the worst case. We present a variation of the FIR filter bank algorithm, applying filter coefficients in a tilted fashion to slow-time signals (i.e., combining slow-time and fast-time). An appropriate tilt, which depends on the flow angle and velocity, corrects for the increased energy under the frequency bands. In this case, the energy under the lowest frequency band filter for an angle of +/- 10 degrees and velocities ranging from 200 mm/s to 300 mm/s is 2.09 to 2.94 times higher than for perpendicular flow, yielding greater than a factor of three improvement in the worst case over the original slow-time method. Moreover, the average energy over the vessel determined with the appropriate tilt is within 2-3% of the true value.

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