Aggression, physical activity levels and sex role identity in teenagers exposed in utero to MPA

The Jerusalem Perinatal Study cohort, 1964–2005: methods and a review of the main results

“…A few minor differences were found comparing MPA‐exposed and non‐exposed offspring, most being due to the more favourable distribution of social variables in the exposed group. The study provided data on the prevalence of various health conditions in teenagers, on factors associated with puberty, and on gender‐dimorphic measures of cognitive ability, aggression and behaviour in school 13–15,76 …”

“…In the 1960s and 1970s, pregnant and parturient women gave verbal consent to being interviewed, and administrative approvals for the studies were obtained from the Ministry of Health, the Jerusalem District Health Office, the Jerusalem Municipality and the individual hospitals. In the 1980s, written informed consent was obtained from the mothers and 18‐year‐old teenagers for the studies of long‐term effects of medroxyprogesterone acetate 13–15 . Since the 1990s, all work on the cohort carried out at the Hebrew University of Jerusalem, and by our collaborators in New York, has been in compliance with the Helsinki Declaration and has been approved by Institutional Review Boards at Hadassah‐Hebrew University Hospital, the Hebrew University of Jerusalem, Columbia University and/or New York University.…”