Aggressive Angiomyxoma

Sutton, Brian J.; Laudadio, Jennifer

doi:10.5858/arpa.2011-0056-rs

Cited by 135 publications

(185 citation statements)

References 28 publications

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“…Estrogen and progesterone receptors are also detected in some cases. Mainly because of the benign characters, the recurrent tumor has similar features with the primary one [1,9,10].…”

Section: Figure 4bmentioning

confidence: 99%

Aggressive Angiomyxoma: Two Case Reports and Review of the Literature

Cao¹

2017

Int J Radiol Imaging Technol

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Aggressive Angiomyxoma (AA) is a kind of rare, low grade myofibroblastic neoplasm with high risk of local recurrence mainly for the character of locally aggressive and misdiagnosis as other soft tissue mass in the pelvis. The "laminated or swirled sign" of swirled strands of low-signal intensities in T2WI is the diagnostic sign for the layered configuration of AA. We report two cases with contrast enhanced CT and Dynamic Contrast Enhancement (DCE) MRI to show the characteristic imaging features and our findings about AA in enhanced CT and DCE MRI. KeywordsAggressive Angiomyxoma (AA), Laminated or Swirled Sign, Magnetic Resonance Imaging (MRI), X-ray Computed Tomography (X-ray CT), Multiplanner Reformation (MPR), Diffusion Weighted Imaging (DWI), Apparent Diffusion Coefficient (ADC) Case RepoRt Case OneA 29-year-old woman was incidentally found a mass in her vagina. She was asymptomatic and was diagnosed as fibroma by biopsy. The CTs can show a well-limited mass with low density compared to muscle located in the left pelvic cavity (Figure 1a). After iodine contrast injection, the mass showed a progressive and heterogeneous enhancement without any layered character (Figure 1b). MRI showed a big mass extending into the obturator foramen and ischiorectal fossa, displacing the gluteus, uterus and vagina without invading (Figure 2a). The mass showed ho-

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“…Estrogen and progesterone receptors are also detected in some cases. Mainly because of the benign characters, the recurrent tumor has similar features with the primary one [1,9,10].…”

Section: Figure 4bmentioning

confidence: 99%

Aggressive Angiomyxoma: Two Case Reports and Review of the Literature

Cao¹

2017

Int J Radiol Imaging Technol

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“…It can be positive for estrogen and progesterone receptors and it has been noted that there may be a chromosomal translocation at 12q13-15 band involving the High Mobility Group AT-Hook 2 (HMGA2) gene. Due to the tumor cells being positive for estrogen and progesterone receptors, some cases have been reported being responsive to Gonadotropin-releasing hormone (GnRH) agonist [2].…”

Section: Discussionmentioning

confidence: 99%

Aggressive Angiomyxoma: A Rare Presentation

Patel¹,

Ali²

2016

JCR

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Abstract:Aggressive angiomyxoma is an uncommon mesenchymal tumor of pelvic area and is usually found to have local invasiveness. It is more commonly found in females and mostly involves pelvis, vulva, vagina, perineum, and urinary bladder. Due to its rare nature there is lack of single clearly beneficial and affective treatment option for this tumor. In the following case report, we discuss the case of a 41 year old female who was seen for an annual gynecological exam and was found to have a vulvar mass upon examination.

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“…Насколько это критично? В проведенных ранее исследованиях [1,14] показано, что максимально радикальное и неполное удаление опухоли даже без проведения лучевой и химиотера-пии одинаково часто сопровождается рецидивом опухолевого роста -до 30-40%. В связи с этим все пациенты, независимо от размеров опухоли и объема проведенной операции, подлежат наблюдению на протяжении продолжительного времени (десятиле-тия) с проведением МРТ в динамике.…”

Section: Discussionunclassified