Aggressive angiomyxoma of the vulva

Amin, Ali; Badawy, S El; Bull, A D

doi:10.3109/01443615.2012.731456

Cited by 10 publications

(7 citation statements)

References 8 publications

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“…Since the rarity of vulvar tumors, we recommend management in team work under the GYN-Oncologist leadership. Nearly all authors believes complete resection of tumor with tumor free margin reduces recurrence rate (16)but according to further investigations, 50 %–70 % relapse are reported after surgical resection [ 17 ]. Recurrences may occur from months to several years after excision (2 months–15 years) [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Aggressive angiomyxoma of vulva in 28-years old patient: A case report of second recurrence

Zamani

Mollabashi

Mehrabi

et al. 2021

Annals of Medicine &Amp; Surgery

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Introduction Aggressive angiomyxoma is an uncommon mesenchymal tumor in women who are in reproductive age, that occurring in the pelvis and perineal zone with a high risk of local infiltration and recurrence. Case presentation We describe a case of a 28-year-old woman with a huge recurrent vulvar aggressive angiomyxoma. Clinical Discussion Our patients underwent surgery and tumor resection for two times but had relapsed every 2 years through 5 years and finally she underwent total vulvectomy. The patient received Decapeptide for 3 months to prevent tumor recurrence after surgery and to date,there has been no evidence of local recurrence. Conclusion Aggressive angiomyxoma is a rare tumor with high recurrence rate. The best treatment is surgical resection by experienced Gyn-oncologist in teamwork and territory Hospital.

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Section: Discussionmentioning

confidence: 99%

Aggressive angiomyxoma of vulva in 28-years old patient: A case report of second recurrence

Zamani

Mollabashi

Mehrabi

et al. 2021

Annals of Medicine &Amp; Surgery

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“…The pathogenesis of AA is still unclear. However, a translocationof chromosome 12 has been implicated as a possible cause [7,28,29]. This translocation results in an aberrant expression of the high mobility group protein isoform I-C (HMGI-C) protein that is involved in DNA transcription [30,31].…”

Section: Discussionmentioning

confidence: 99%

Untitled

2016

OGIJ

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“…AAM occurs mainly in the pelvis, perineum, vulva, vagina, and urinary bladder, and may exert pressure on adjacent organs. Appropriate management and long-term follow-up of this tumor should be considered owing to its locally aggressive nature [ 4 ]. This tumor also involves the blood vessels.…”

Section: Discussionmentioning

confidence: 99%

Alternative surgical approaches for aggressive angiomyxoma at different sites in the pelvic cavity

Choi

Park

2015

Obstet Gynecol Sci

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Aggressive angiomyxoma, a rare soft tissue benign neoplasm, predominantly occurs in the female pelvic peritoneum and perineum region during reproductive age. It is slow growing, locally infiltrative, and has a high risk of local recurrence and the neoplastic character of blood vessels. The standard treatment is surgery. We report three unusual aggressive angiomyxoma cases. The first case was a pedunculated mass of the left labium major; the second, a left perineal mass that infiltrated into the paravesical area via the obturator foramen; and the third, a big mass in the retroperitoneal cavity, found that growing aggressive angiomyxoma looked like lava expulsion in the pelvic area. After a thorough examination and full radiologic workup, we performed surgical excision in each patient via different approaches. Histopathologic findings were consistent with diagnosis of aggressive angiomyxoma. To date, no relapse has been observed.

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Aggressive angiomyxoma of the vulva

Cited by 10 publications

References 8 publications

Aggressive angiomyxoma of vulva in 28-years old patient: A case report of second recurrence

Aggressive angiomyxoma of vulva in 28-years old patient: A case report of second recurrence

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Alternative surgical approaches for aggressive angiomyxoma at different sites in the pelvic cavity

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