Aggressive atypical ameloblastic fibrodentinoma: Report of a case

Abstract

Ameloblastic fibroma and related lesions constitute a group of lesions, which range in biologic behaviour from true neoplasms to hamartomas. This group of lesions is also sometimes referred to as mixed odontogenic tumors and usually includes ameloblastic fibroma, ameloblastic fibrodentinoma and ameloblastic fibro-odontoma. Despite numerous efforts however, there is still considerable confusion concerning the nature and interrelationship of these mixed odontogenic tumors and related lesions. The malignant counterpart of these lesions namely aameloblastic fibrosarcoma, ameloblastic dentinosarcoma and ameloblastic odontosarcoma respectively are said to arise secondarily in their benign counterpart or de novo. Recurrence of the benign lesion raises the risk towards malignant transformation therefore a radical surgery should be planned inspite of enucleation or curettage. Here we present a case of an aggressive ameloblastic fibrodentinoma which was radically excised in the light of clinical and histological presentation followed by reconstruction of mandible.

Ameloblastic Fibrodentinoma: Report of a Case in an Infant

“…In this case the lesion was associated with crown of a unerputed canine. AFD is generally seen in young adults with males more commonly affected than females with a predilection of 3:1 [7]. In the present case the child was just one-year-old.…”

Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination

“…Several cases of AFO have been reported in the literature (3,6,8,10,11,(13)(14)(15)(16)(17)(18)(19) and it is known to frequently affect individuals below 16 years of age (1,8,20,21). One study has indicated that, when compared with ameloblastic fibroma, AFO more commonly affects individuals belonging to the younger age group; however, this claim can be refuted (19).…”

Ameloblastic fibro-odontoma located in the maxilla of a 3-year-old girl

“…Interestingly, patients coming from countries such as India [19,20] or South America [11,21,22] present to dentists often at teenage or adult age whereas in countries such as Germany [23,24] or Switzerland, tumors are detected much earlier. An important explanatory reason may be the fact that the latter countries have well developed health care systems and dental examinations are offered in early childhood.…”

“…As reported above a small part of the maxillary sinus was exposed and partially involved in the surgical resection. A more aggressive treatment as described by Girradi concerning fibrodentinoma [20] is not recommended because of increased morbidity. Especially in the mandible, the risk of a pathological fracture is very high when performing a marginal resection and thus cannot be supported when compared to a more conservative procedure of tumor tissue removal [14].…”