Aggressive Fibromatosis of the Chest Wall

Huang, Chao‐Cheng; Ko, Sheung‐Fat; Yeh, Ming-Chung; Ng, Shu‐Hang; Huang, Hsuan‐Ying; Lee, Chih-Chia; Lee, Tze‐Yu

doi:10.7863/jum.2009.28.3.393

Cited by 12 publications

(9 citation statements)

References 11 publications

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“…It is the study of choice for pregnant patients and to guide biopsies. The appearance differs from a smooth contour oval mass to a poorly defined soft tissue tumor with variable echogenicity [ 23 ]. There are two characteristic signs that can be identified: the “tail sign” is a linear extension into the fascial planes, and the “staghorn sign” caused by the intramuscular digitiform projections of the tumor [ 24 ].…”

Section: Image Studiesmentioning

confidence: 99%

Desmoid-Type Fibromatosis

García-Ortega

Martín-Tellez²,

Cuéllar-Hübbe

et al. 2020

Cancers

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Desmoid tumors represent a rare entity of monoclonal origin characterized by locally aggressive behavior and inability to metastasize. Most cases present in a sporadic pattern and are characterized by a mutation in the CTNNB1 gene; while 5–15% show a hereditary pattern associated with APC gene mutation, both resulting in abnormal β-catenin accumulation within the cell. The most common sites of presentation are the extremities and the thoracic wall, whereas FAP associated cases present intra-abdominally or in the abdominal wall. Histopathological diagnosis is mandatory, and evaluation is guided with imaging studies ranging from ultrasound, computed tomography or magnetic resonance. Current approaches advocate for an initial active surveillance period due to the stabilization and even regression capacity of desmoid tumors. For progressive, symptomatic, or disabling cases, systemic treatment, radiotherapy or surgery may be used. This is a narrative review of this uncommon disease; we present current knowledge about molecular pathogenesis, diagnosis and treatment.

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Section: Image Studiesmentioning

confidence: 99%

Desmoid-Type Fibromatosis

García-Ortega

Martín-Tellez²,

Cuéllar-Hübbe

et al. 2020

Cancers

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“…Lesions may demonstrate prominent posterior acoustic shadowing [47, 48]. One author describes visualizing a “fascial tail” sign and staghorn pattern with the use of high frequency ultrasound probes [53]. The “fascial tail” sign denotes linear tumor extension along the fascial planes and is described further in the section on MR imaging.…”

Section: Extraabdominal Fibromatosismentioning

confidence: 99%

Imaging Features of Superficial and Deep Fibromatoses in the Adult Population

Walker

Petscavage

Brian

et al. 2012

Sarcoma

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The fibromatoses are a group of benign fibroblastic proliferations that vary from benign to intermediate in biological behavior. This article will discuss imaging characteristics and patient demographics of the adult type superficial (fascial) and deep (musculoaponeurotic) fibromatoses. The imaging appearance of these lesions can be characteristic (particularly when using magnetic resonance imaging). Palmar fibromatosis demonstrates multiple nodular or band-like soft tissue masses arising from the proximal palmar aponeurosis and extending along the subcutaneous tissues of the finger in parallel to the flexor tendons. T1 and T2-weighted signal intensity can vary from low (higher collagen) to intermediate (higher cellularity), similar to the other fibromatoses. Plantar fibromatosis manifests as superficial lesions along the deep plantar aponeurosis, which typically blend with the adjacent plantar musculature. Linear tails of extension (“fascial tail sign”) along the aponeurosis are frequent. Extraabdominal and abdominal wall fibromatosis often appear as a heterogeneous lesion with low signal intensity bands on all pulse sequences and linear fascial extensions (“fascial tail” sign) with MR imaging. Mesenteric fibromatosis usually demonstrates a soft tissue density on CT with radiating strands projecting into the adjacent mesenteric fat. When imaging is combined with patient demographics, a diagnosis can frequently be obtained.

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“…Some radiological signs that can help radiologist to diagnose a DT are as follows: “Staghorn sign” due to intramuscular finger-like extensions [ 26 ]. …”

Section: Extra-abdominal Dtmentioning

confidence: 99%

Multimodality imaging features of desmoid tumors: a head-to-toe spectrum

et al. 2020

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Desmoid tumors (DTs) are a rare and biologically heterogeneous group of locally aggressive fibroblastic neoplasm: their biological behavior spectrum ranges from indolent to aggressive tumors. DTs are classified as intra-abdominal, extra-abdominal, and within the abdominal wall lesions. It is well known that abdominal and extra-abdominal DTs are associated with familial adenomatous polyposis (FAP) and Gardner syndrome. Possible risk factors are prior trauma/surgery, pregnancy, and oral contraceptives. There was a real revolution in the management of DT: from aggressive first-line approach (surgery and radiation therapy) to a more conservative one (systemic treatment and “wait-and-see policy”). In these clinical settings, radiologists play an important role for assessing lesion resectability, evaluating recurrence, monitoring the biological behavior if an expectant management is chosen, and assessing response to systemic treatment as well as to radiation therapy. Awareness of common locations, risk factors, and imaging features is fundamental for a correct diagnosis and an adequate patient management.

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Aggressive Fibromatosis of the Chest Wall

Cited by 12 publications

References 11 publications

Desmoid-Type Fibromatosis

Desmoid-Type Fibromatosis

Imaging Features of Superficial and Deep Fibromatoses in the Adult Population

Multimodality imaging features of desmoid tumors: a head-to-toe spectrum

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