Aging, geroproteсtors, gene therapy

Dzhaparidze, L. A.

doi:10.30694/1026-5600-2019-2-109-123

Regecology

2019

DOI: 10.30694/1026-5600-2019-2-109-123

|View full text |Cite

Aging, geroproteсtors, gene therapy

L. A. Dzhaparidze¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Preprint1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Effect of quercetin and kaempferol isolated from theGinkgo bilobaL. suspension culture extract on lipofuscin accumulation

Milentyeva

Fedorova

Vesnina

et al. 2023

Preprint

View full text Add to dashboard Cite

Lipofuscin, known as an age pigment, is an autofluorescent lipopigment formed by lipids, metals, and misfolded proteins that accumulates in nerve cells, heart muscle cells, and skin. Individual bioactive compounds obtained from medicinal plant extracts reduce the level of lipofuscin in C. elegans nematodes in in vivo experiments. We aimed to study the effect of quercetin and kaempferol isolated from the in vitro suspension culture extracts of Ginkgo biloba L. on the accumulation of lipofuscin. According to the results, 200 micromole concentrations of these bioactive compounds showed the maximum decrease in lipofuscin levels in C. elegans N2 Bristol during their 15-day cultivation, compared to the control. Thus, our study showed that quercetin and kaempferol are able to reduce this age pigment in in vivo experiments.

show abstract

Effect of quercetin and kaempferol isolated from theGinkgo bilobaL. suspension culture extract on lipofuscin accumulation

Milentyeva

Fedorova

Vesnina

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Aging, geroproteсtors, gene therapy

Cited by 1 publication

References 45 publications

Effect of quercetin and kaempferol isolated from theGinkgo bilobaL. suspension culture extract on lipofuscin accumulation

Effect of quercetin and kaempferol isolated from theGinkgo bilobaL. suspension culture extract on lipofuscin accumulation

Contact Info

Product

Resources

About