Aging Increases Compensatory Saccade Amplitude in the Video Head Impulse Test

Anson, Eric; Bigelow, Robin T.; Carey, John P.; Qin, Xue; Studenski, Stephanie A.; Schubert, Michael C.; Weber, Konrad P.; Agrawal, Yuri

doi:10.3389/fneur.2016.00113

Cited by 54 publications

(69 citation statements)

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“…They reportd that the presence of covert saccades despite normal VOR gain is a correction of eye drifts to the target position and it has been suggested that the presence of refixation saccades with normal VOR gain is part of the process of aging of the vestibular system. 23 Yollu et al, 24 reported significantly higher covert saccades in migraine patients compared to healthy controls, and suggested that these saccades were associated with the connection between the trigeminal nerve and the vestibular nuclei.…”

Section: Discussionmentioning

confidence: 99%

Video head impulse test finding in vestibular lesions

Ismail¹,

Behairy²,

Brakat³

2019

JOENTR

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Introduction of video head impulse test (vHIT) as a new objective quantitative test of vestibular function, provides a new dimension in vestibular evaluation. 1vHIT is a simple fast clinical vestibular test. It has the ability to detect specific vestibular lesion by using physiologic high frequency stimuli and measure the gain of the vestibulo-occular reflex (VOR). If there is abnormal VOR response, the test can measure the gain of VOR and detect any refixation saccade (overt and covert saccades. 2The vestibular hair cells respond to frequencies from 0 to 16 Hz, being particularly active in the range of 0.1-10 Hz. The caloric test is usually in the area ranging from 0.003 to 0.05 Hz, but rotational tests are in the area of high frequencies. 3 The vHIT is a more physiological stimulus testing higher frequencies (>1Hz) Heuberger et al. 4 It is therefore possible that a subject may have a normal caloric test, but manifest VOR deficits during head movements within a higher frequency range. 5 Bartolomeo et al., 6 found the sensitivity of vHIT increased up to 86.7 % and specificity to 100 % when the caloric deficit is between 40 and 65 % in case of VN. The sensitivity of vHIT increased to 100 % if caloric deficit is more than 65.2 %. McCaslin et al., 7 found dissociation between caloric test and vHIT in MD as caloric tests showed a vestibular deficit, while the vHIT was normal in 45 % of the cases. Manzari et al., 8 reported an enhanced vHIT lateral canal gain response in all 13 Meniere's patients tested at attack and in 18 of 30 patients tested during quiescence. Their hypothesis was that the enlarged endolymph volume causes enhanced displacement and enhanced return of the cupula which might lead to enhanced response in MD patients.Caloric testing and the video head impulse test (vHIT) are reliable tests, caloric testing can evaluate the function of the lateral semicircular canal and superior vestibular nerve, However, vHIT can detect abnormalities in all six semicircular canals and it can be used in patients who do not tolerate caloric test such as some elder patient, children or patient with perforated tympanic membrane. 9 The vHIT can be used as a screening tool for vestibular deficits due to gentamicin toxicity. 10The simplicity of vHIT and its relatively innocuous character for patients means that it can be used even during vertigo attacks. So it has been used to show in patients with Menière's disease how semicircular canal function fluctuates during and around the time of the attack of vertigo Manzari et al. 8 Also there is need to have objective measure of the VOR during HIT by using a system fast enough and accurate enough to detect any type of saccades because some patients were missed by bedside head impulse test, even by expert examiners. 11 So this study is conducted to compare video head impulse test results among different vestibular lesions and healthy subjects and correlate between video head impulse test and caloric test results. MethodsThis study was carried out in the Audio vestibular unit at the A...

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Section: Discussionmentioning

confidence: 99%

Video head impulse test finding in vestibular lesions

Ismail¹,

Behairy²,

Brakat³

2019

JOENTR

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“…Saccade amplitude usually correlates with gain deficit in peripheral vestibulopathy; 3,43 however, one particular pattern, "normal gain with catch-up saccade," is a well recognized exception, which is associated with increasing age, thought to be because of the slight gain reduction, gaze positional error correction independent of VOR, and inability to suppress saccades to novel targets. 47,48…”

Section: Performing Vhitmentioning

confidence: 99%

Video Head Impulse Testing: From Bench to Bedside

Chen

Hálmagyi

2020

Semin Neurol

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Over 30 years ago, the head impulse test (HIT) was measured with search coil recordings and it provided robust evidence for a new test of vestibular function that could detect impairment of a single semicircular canal, that is, the lateral canal. Over the next two decades, the diagnostic spectrum of HIT was expanded to the testing of vertical canals, differentiation of central from peripheral vestibulopathy, and incorporation of visual interaction—the suppressed head impulse. However, HIT measurement was limited to very few specialized laboratories that were able to maintain the time-consuming and expensive operation of the scleral search coil system, which is the gold standard in eye movement recording. The video HIT (vHIT) was validated for the first time over 10 years ago, against the search coils, and its introduction into dizzy clinics worldwide has revolutionized the practice of neuro-otology. Here we review the basic physiology, practical aspects, and clinical application of the vHIT.

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“…Kompensatorische Sakkaden zeigten keine Altersabhängigkeit. Auch andere Arbeitsgruppen konnten eine Reduktion des Gainwertes im höheren Lebensalter ( > 70) nachweisen [146][147][148][149]. Anson et al wiesen auf den Zusammenhang einer Gainreduktion mit einer Zunahme der Amplitude von Korrektursakkaden im Alter hin.…”

Section: Bewertung Der Ergebnisseunclassified

“…Anson et al wiesen auf den Zusammenhang einer Gainreduktion mit einer Zunahme der Amplitude von Korrektursakkaden im Alter hin. Dies wird mit einer Beeinträchtigung hochfrequenter, irregulärer vestibulärer Typ-1-Fasern durch "Altersprozesse" erklärt [146,147]. Die Interpretation im höheren Lebensalter (ca.…”

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Moderne Schwindeldiagnostik

Walther

2017

Laryngo-Rhino-Otol

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Modern diagnostic methods such as video head impulse test and cervical and ocular vestibular evoked myogenic potentials allow to measure canal and otolith function quantitatively and objectively. These methods contribute to a complex assessment of the functional integrity of all 5 sensory elements of the vestibular organ for the first time. Moreover, in combination with additional vestibular tests frequency specific and time depended changes of impairments of vestibular sensors and their pathways can be assessed. Over the past few years, new test methods have been established step by step in daily clinical diagnostic of vertigo and dizziness in acute vestibular syndrome and chronic complaints. Modern tests and concepts caused a paradigm shift in vestibular diagnostic. New classifications of vestibular disorders and algorithms provide a high diagnostic certainity and reliability although evidence-based investigations of diagnostic procedures are still missing.

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Aging Increases Compensatory Saccade Amplitude in the Video Head Impulse Test

Cited by 54 publications

References 41 publications

Video head impulse test finding in vestibular lesions

Video head impulse test finding in vestibular lesions

Video Head Impulse Testing: From Bench to Bedside

Moderne Schwindeldiagnostik

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