Aging is inevitable: understanding aging anxiety related to physical symptomology and quality of life with the mediating role of self-esteem in adults

Yawar, Rowaida; Khan, Soulat; Rafiq, Maryam; Fawad, Nimra; Shams, Sundas; Navid, Saher; Khan, Muhammad Abdullah; Taufiq, Nabiha; Touqir, Areesha; Imran, Moazma; Butt, Tayyab Ali

doi:10.1108/ijhrh-05-2022-0047

Cited by 5 publications

(4 citation statements)

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“…Elevated anxiety levels have also been linked to lower QoL in seniors [ 68 ]. Additionally, ageing anxiety has been identified as a predictor of death anxiety, further contributing to a lower QoL [ 69 ].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Three-Month Quercetin Intake on Quality of Life and Anxiety in Patients With Type II Diabetes Mellitus: An Early Data Analysis From a Randomized Controlled Trial

Mantadaki,

Linardakis,

Vafeiadi

et al. 2024

Cureus

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Background: Diabetes is a high-prevalence, major chronic metabolic disease demanding effective interventions. Quercetin, a phytochemical with potential health benefits, has garnered interest for its therapeutic properties. Aim: This study was designed to capture the early efficacy and clinical safety aspects following quercetin administration in patients with type II diabetes mellitus (T2DM). Methods: The main study involved a randomized allocation procedure to assign non-insulin-treated patients attending the 4th Health Unit of Heraklion to intervention and control groups based on age and sex. The intervention group (n=50) received 500 mg of quercetin daily for 12 + (8 free intervals) + 12 weeks, alongside their usual treatment, while the control group (n=50) did not. After randomization, for the intermediary 12-week follow-up, data from 38 patients (intervention: 20; control: 18) were analyzed in this report. All subjects provided informed consent for the collection of anthropometric measurements, vital signs, daily habits data, and PiKo-6 spirometric readings. Additionally, participants responded to the Short Anxiety Screening Test (SAST) and the 36-Item Short Form Health Survey (SF-36) questionnaires. Results: Thirty-eight participants were included (60% men and 40% women in the intervention group; 38.9% men and 61.1% women in the control group). In the treatment arm, Forced Expiratory Volume in the first second (FEV 1 ) measured with PiKo-6 showed a Δ %- change for the intervention arm: +6.8%, control: -0.2% (p=0.059), systolic blood pressure; intervention: -7.4%, control: -3.7% (p=0.117), waist circumference; intervention: -1.5% control: -0.7% (p=0.455) and night-time sleep; intervention: +5.3%, control: +1.4% (p=0.926) were favourably influenced. The treatment group exhibited significant enhancements in both anxiety levels assessed by the anxiety symptoms scale (SAST-10, p=0.026) and quality of life evaluated by the SF-36 (p<0.001). Conclusions: Positive evidence is emerging for a pleiotropic effect of quercetin intake in patients with T2DM, specifically in terms of anxiety reduction and amelioration of life quality, in just 12 weeks of administration and without adverse effects, indicating clinical safety and underscoring its potential for integration in T2DM supportive care.

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Section: Discussionmentioning

confidence: 99%

The Impact of Three-Month Quercetin Intake on Quality of Life and Anxiety in Patients With Type II Diabetes Mellitus: An Early Data Analysis From a Randomized Controlled Trial

Mantadaki,

Linardakis,

Vafeiadi

et al. 2024

Cureus

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“…Furthermore, higher anxiety levels have been linked to poorer QoL in older populations [ 103 ]. Notably, anxiety related to aging itself has been implicated in a decline in QoL [ 104 ]. The importance of prioritizing QoL enhancements within diabetes management protocols is underscored.…”

Section: Discussionmentioning

confidence: 99%

Benefits of Quercetin on Glycated Hemoglobin, Blood Pressure, PiKo-6 Readings, Night-Time Sleep, Anxiety, and Quality of Life in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Mantadaki,

Linardakis,

Tsakiri

et al. 2024

JCM

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Background: Diabetes is a rapidly growing global morbidity issue with high prevalence, and the associated dysglycemia leads to complications. Patients with type 2 diabetes mellitus (T2DM) often experience elevated anxiety levels, affecting their quality of life and diabetes management. This study investigated quercetin, a nutraceutical and potential senolytic with antioxidant activity, to detect its possible positive effect on the bio-clinical measurements and routine health of patients with T2DM. Methods: This prospective randomized controlled trial (RCT) investigated the clinical usefulness of quercetin in patients with T2DM receiving non-insulin medications. One hundred participants were stratified by age and sex (1:1) and randomized to control (n = 50) or intervention (n = 50) groups. The control received standard care only, while the intervention received 500 mg quercetin daily for 12 weeks, followed by an 8-week washout and a final consecutive 12-week supplementation period (total: 32 weeks), as adjunct to their usual care. Comprehensive health assessments, including blood analyses, were conducted at baseline and study termination. Quality of life and anxiety were assessed using the 36-item Short Form Health Survey (SF-36) and Short Anxiety Screening Test (SAST-10). Results: Eighty-eight patients with T2DM concluded the trial. Compared with the control, glycated hemoglobin (HbA1c) levels showed a significant decrease (Δ%-change: −4.0% vs. 0.1%, p = 0.011). Quercetin also significantly improved PiKo-6 readings (FEV1: 5.6% vs. −1.5%, p = 0.002), systolic blood pressure (−5.0% vs. −0.2%, p = 0.029), night-time sleep (11.6% vs. −7.3%, p < 0.001), anxiety levels (SAST-10) (−26.2% vs. 3.3%, p < 0.001), and quality of life (SF-36) (both physical and mental components, p < 0.001). Conclusions: Based on the current open-label study, quercetin appears to be a promising supplement for T2DM, providing lifestyle and care support. Further research is warranted to shift this potential from clinical usefulness and feasibility to multidisciplinary evidence.

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“…However, since aging has long been synonymous with declining health ( Lindland et al, 2015 ; Sweetland et al, 2017 ), some may have posed such queries to feel a greater sense of control over their health, or to cope with the anxiety about the physical or cognitive changes that come with growing older. When left unchecked, this anxiety can affect one’s quality of life ( Yawar et al, 2022 ).…”

Section: Discussionmentioning

confidence: 99%

Questions About Aging and Later Life on Quora

Ng,

Indran

2024

The Gerontologist

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Background and Objectives Gerontologists have yet to explore the types of questions individuals have about later life. Analyzing questions offers a unique perspective on how individuals make sense of age-related issues. Specifically, questions require people to articulate specific inquiries or doubts, thus providing an unfiltered glimpse into the public’s concerns and priorities vis-à-vis aging. We conduct a content analysis of questions posted on Quora that pertain to later life. Research Design and Methods We compiled 2,950 questions posted across four topics on Quora: ‘Aging’, ‘Senior Citizens’, ‘Elders’ and ‘Older People’. After applying our exclusion criteria, 658 questions were left for content analysis. These questions received over 250 million views. Both deductive and inductive approaches guided our qualitative analysis. Results Five themes emerged from our analysis. The biggest theme (30%; N=195) dealt with ‘Practical Concerns’ (Theme 1). The next biggest theme (29%; N=191) was about ‘Health and Well-Being’ (Theme 2). Theme 3 was about the ‘Prolongation of Youth’ (16%; N=110) and Theme 4 was about the ‘Science of Aging’ (15%; N=97). Theme 5 covered ‘Existential Concerns’ (10%; N=65). Discussion and Implications There is a need to address concerns that the public has about aging, particularly those involving practical issues and health. Growing old is unavoidable and with the population aging at a rapid pace, assuaging such concerns is of paramount importance. By doing so, individuals can approach the aging process with greater clarity and an elevated sense of empowerment.

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Aging is inevitable: understanding aging anxiety related to physical symptomology and quality of life with the mediating role of self-esteem in adults

Cited by 5 publications

References 50 publications

The Impact of Three-Month Quercetin Intake on Quality of Life and Anxiety in Patients With Type II Diabetes Mellitus: An Early Data Analysis From a Randomized Controlled Trial

The Impact of Three-Month Quercetin Intake on Quality of Life and Anxiety in Patients With Type II Diabetes Mellitus: An Early Data Analysis From a Randomized Controlled Trial

Benefits of Quercetin on Glycated Hemoglobin, Blood Pressure, PiKo-6 Readings, Night-Time Sleep, Anxiety, and Quality of Life in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Questions About Aging and Later Life on Quora

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