Agreement between Colposcopic Diagnosis and Cervical Pathology: Siriraj Hospital Experience

Abstract

Asian Pac J Cancer Prev, 15 (1), [423][424][425][426] IntroductionCervical cancer is the second most common malignancy in women worldwide after breast cancer (Ferlay et al.). In Thailand, its incidence was 17.7/100,000 of Thai female population during (Khunhaprema et al., 2012. Cervical cancer incidences and deaths have decreased since the implementation of widespread cervical cancer screening with cervical cytology and/or human papilloma virus (HPV) (Saslow et al., 2012). The knowledge of HPV has been advanced. However, the cervical cytology is still the mainstay of cervical cancer screening. Colposcopy is the next investigation step for abnormal cervical screening patients after the followings; a) two consecutive unsatisfactory cytology results; b) most cases of positive HPV testing; c) repeated atypical squamous cell of undetermined significance (ASC-US) cytology; d) low grade squamous intraepithelial lesion (LSIL) cytology; e) atypical squamous cell, cannot exclude high grade squamous intraepithelial lesion (ASC-H) cytology; f) high grade squamous intraepithelial lesion (HSIL) cytology; g) some types of glandular abnormality (Massad et al., 2013

Diagnostic value of the 2011 International Federation for Cervical Pathology and Colposcopy Terminology in predicting cervical lesions

“…The study results showed that the agreement of the colposcopic diagnosis and cervical biopsy pathology was perfectly matched in 65.5% of lesions, further, the agreement of the colposcopic diagnosis and final pathology was perfectly matched in 66.2% of lesions, with findings significantly better than those of Baum et al and Massad et al (perfect agreement, 32-37%) [ 3 , 4 ]. Tatiyachonwiphut et al [ 13 ] reported an exact agreement of 57.9%, one grade agreement of 94.1%, and a weighted kappa strength of agreement of 0.494, which were comparable to the results of our study. However, the study lacked a standard criterion or scoring system for colposcopic examination.…”

Closer to a Uniform Language in Colposcopy: Study on the Potential Application of 2011 International Federation for Cervical Pathology and Colposcopy Terminology in Clinical Practice

“…Instead, the other three methods were substantially unequivalent between them. This is especially the case with the modified RCI and Swede Score, where the underestimated diagnoses were rather high, consistent with approximately 1/3 of HSIL underdiagnosed colposcopies in other reports [27, 28]. …”

A comparison of the associations of Reid Colposcopic Index and Swede Score with cervical histology

“…After an abnormality is detected through cervical screening, a colposcopy is performed . In a previous Siriraj Hospital study, the false‐negative rate using a colposcopy alone was determined to be 19.1% . That study suggested using a cervical biopsy as the gold standard to detect high‐grade lesions.…”

“…[3][4][5][6][7] In a previous Siriraj Hospital study, the false-negative rate using a colposcopy alone was determined to be 19.1%. 8 That study suggested using a cervical biopsy as the gold standard to detect highgrade lesions. Furthermore, a study from Germany found that the accuracy by colposcopy was only 85.8%.…”