Agreement in surfactant measurements of sputum induced with hypertonic and normal saline

Abstract

We conclude that DPPC concentration of sputum can be easily measured in induced sputum and that the use of hypertonic saline does not influence the DPPC levels.

‘Free’ surfactant in gastric aspirates and bronchoalveolar lavage in children with and without reflux oesophagitis

“…DPPC can be adsorbed (reversibly bound) onto the epithelial layer or occur in the ‘free’ state 8 . We have previously shown that free DPPC can be easily measured in airways 10,11 and that increased DPPC is associated with increased eosinophilic inflammation in children with asthma, 11 possibly as an inherent lung mechanism for epithelial protection. Animal studies have shown that DPPC levels progressively increase in response to chronic lung injury 9,12 …”