Changes in land use are reflected primary in changes of land cover, but subsequently cause conflict of interest of sectors and are the main initiation of many environmental problems. The basic tool for sustainable utilization of the landscape is integrated landscape management, which, in our understanding, is the environmentally biased harmonization of tools which regulate the spatial organization and functional utilization of the landscape to avoid the conflicts of interest of sectors. "Integrated" in this case means the systematic assessment of the interests of all relevant sectors from the environmental point of view. The scientific base of this approach is the understanding of the landscape as a geosystem, and, in particular, the proper interpretation of the mutual relations of primary, secondary and tertiary landscape structures and their role in the assessment of the conflicts of interest. This paper presents a theoretical and methodical base for the integrated approach to the assessment of the conflicts of interest of the sectors in the landscape. The theoretical-methodical base was applied to the model territory of the Trnava district (south-west Slovakia). Mutual conflicts of interest of endangering and endangered sectors cause diverse problems, which were ranked in three basic groups as: problems of endangering of the ecological stability of the landscape (including endangering of biodiversity and nature conservation areas); problems of endangering of natural resources (in particular forests, soils, waters); and, problems of endangering the immediate human environment (stress factors in residential and recreational areas). The result is the identification and analysis of the conflicts of interest in the territory and their projection to a map. This research should be followed by implementation of procedures of ecologically optimal spatial organization and utilization of the territory for regular spatial planning processes. of the GMTs are not yet completely known, as many have begun to manifest themselves in recent years. The relationships between individual GMTs raise a large number of questions, and there are still many deficiencies in the knowledge of their impact on the landscape.Several of these environmental global megatrends are initiated by inappropriate land use. According to Food and Agriculture Organization of the Unated Nations (FAO) information, up to 60% of the world's ecosystems are degraded and exploited unsustainably [5]. In the EU, only 17% of habitats and species and 11% of key ecosystems protected by European legislation show a favorable status [4][5][6]. This is despite the adoption of measures in 2001 to combat biodiversity loss. All scenarios of global and regional assessments show that biodiversity loss, degradation of ecosystems and threats to environmental conditions will continue or even accelerate [7]. Human activities, global population growth and changing consumption patterns are key factors responsible for this growing environmental burden, which primarily becomes evident ...