The aim of the paper was to assess the importance of the bilateral turnover to the EU and the US foreign trade in agri-food products in 2001-2016, as well as to define the possibilities of its development after signing the TTIP Agreement. The research is based on the data from the ComExt Database in the resources of the Statistical Office of the European Union (Eurostat) and the USDA Foreign Agricultural Service's Global Agricultural Trade System. It was proved that in 2001-2016 the EU and the US were important trade partners for each other, but the value of bilateral trade in agri-food products remained relatively small, largely due to low complementarity of the Polish and American agriculture and the resulting minor demand for agricultural products from the temperate zone in the US. These products are made in the US, usually at a lower cost, and they are the export surplus of this country. The way to intensify the EU-US bilateral trade may be to develop a transatlantic free trade area, resulting in a strong effect of trade creation between the TTIP parties, with a limited impact on the relationship with other trading partners.