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Prototropic changes in cationic base‐pair adducts. II. Guanine methylation

“…Some time ago, Brooks and Lawley suggested that the mutagenic activities of simple alkylating agents might be due to their propensity to lead to abasic sites [23]. This view was temporarily abandoned when the critical role of base 0-alkylation was discovered [5].…”

Melodrama and its Criticism: An Essay in Memory of Sally Ledger

“…Brooks' central thesis was that 'the melodramatic mode' is a means of 'uncovering, demonstrating, and making operative the essential moral universe in a post-sacred era'. 12 His use of tools like psychoanalysis and expressionism to analyse the melodramatic 'mode' (rather than genre), as it manifested itself in the novels of canonical writers like Balzac and Henry James, was groundbreaking. However, in many ways, Brooks makes melodrama acceptable to literary studies rather than rethinking literary studies via melodrama; he removes melodrama from its original ideological and theatrical contexts and, in framing characters as 'psychic signs', buries the cultural politics of melodrama's lack of interest in the psyche.…”

“…However, in many ways, Brooks makes melodrama acceptable to literary studies rather than rethinking literary studies via melodrama; he removes melodrama from its original ideological and theatrical contexts and, in framing characters as 'psychic signs', buries the cultural politics of melodrama's lack of interest in the psyche. 13 Brooks' work is perhaps atypical of studies of melodrama, however, which can perhaps most helpfully (though heuristically and not exclusively) be seen via three different threads: 'theatrical' studies which focus on theatre as theatre, and/or theatre history; genre studies, which include, but extend beyond, a significant body of work on the The internet is not simply broadening access to the play as print object but also to theatrical 'ephemera' -not in fact ephemeral to scholars' interest in the material conditions and cultural production of nineteenth-century melodrama. …”

“…52 In this sense, Peter Brooks was right to argue that we must 'recognize melodrama as a central fact of the modern sensibility'. 53 For Brooks, melodrama attempts to impart meaning to a post-sacred world:…”

Treatment for low back pain, use of meloxicam

“…Поэтому более безопасны те НПВП, которые не влияют или мало влияют на активность ЦОГ1 [11]. Среди традиционных НПВП препараты, более селективные в от-ношении ЦОГ2, чем ЦОГ1, в 3-4 раза реже вызывают ос-ложнения со стороны желудочно-кишечного тракта (ЖКТ), чем менее селективные [12][13][14].…”